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T-Cell Protein Tyrosine Phosphatase Is Irreversibly Inhibited by Etoposide-Quinone, a Reactive Metabolite of the Chemotherapy Drug Etoposide.
Nian, Qing; Berthelet, Jérémy; Zhang, Wenchao; Bui, Linh-Chi; Liu, Rongxing; Xu, Ximing; Duval, Romain; Ganesan, Saravanan; Leger, Thibaut; Chomienne, Christine; Busi, Florent; Guidez, Fabien; Dupret, Jean-Marie; Rodrigues Lima, Fernando.
Afiliación
  • Nian Q; Université de Paris, BFA, UMR 8251, CNRS, Paris, France (Q.N., J.B., W.Z., L.-C.B., R.L., F.B., J.-M.D., F.R.L.); Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao, China (X.X.); Université de Paris, BIGR, UMRS 1134, IN
  • Berthelet J; Université de Paris, BFA, UMR 8251, CNRS, Paris, France (Q.N., J.B., W.Z., L.-C.B., R.L., F.B., J.-M.D., F.R.L.); Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao, China (X.X.); Université de Paris, BIGR, UMRS 1134, IN
  • Zhang W; Université de Paris, BFA, UMR 8251, CNRS, Paris, France (Q.N., J.B., W.Z., L.-C.B., R.L., F.B., J.-M.D., F.R.L.); Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao, China (X.X.); Université de Paris, BIGR, UMRS 1134, IN
  • Bui LC; Université de Paris, BFA, UMR 8251, CNRS, Paris, France (Q.N., J.B., W.Z., L.-C.B., R.L., F.B., J.-M.D., F.R.L.); Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao, China (X.X.); Université de Paris, BIGR, UMRS 1134, IN
  • Liu R; Université de Paris, BFA, UMR 8251, CNRS, Paris, France (Q.N., J.B., W.Z., L.-C.B., R.L., F.B., J.-M.D., F.R.L.); Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao, China (X.X.); Université de Paris, BIGR, UMRS 1134, IN
  • Xu X; Université de Paris, BFA, UMR 8251, CNRS, Paris, France (Q.N., J.B., W.Z., L.-C.B., R.L., F.B., J.-M.D., F.R.L.); Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao, China (X.X.); Université de Paris, BIGR, UMRS 1134, IN
  • Duval R; Université de Paris, BFA, UMR 8251, CNRS, Paris, France (Q.N., J.B., W.Z., L.-C.B., R.L., F.B., J.-M.D., F.R.L.); Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao, China (X.X.); Université de Paris, BIGR, UMRS 1134, IN
  • Ganesan S; Université de Paris, BFA, UMR 8251, CNRS, Paris, France (Q.N., J.B., W.Z., L.-C.B., R.L., F.B., J.-M.D., F.R.L.); Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao, China (X.X.); Université de Paris, BIGR, UMRS 1134, IN
  • Leger T; Université de Paris, BFA, UMR 8251, CNRS, Paris, France (Q.N., J.B., W.Z., L.-C.B., R.L., F.B., J.-M.D., F.R.L.); Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao, China (X.X.); Université de Paris, BIGR, UMRS 1134, IN
  • Chomienne C; Université de Paris, BFA, UMR 8251, CNRS, Paris, France (Q.N., J.B., W.Z., L.-C.B., R.L., F.B., J.-M.D., F.R.L.); Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao, China (X.X.); Université de Paris, BIGR, UMRS 1134, IN
  • Busi F; Université de Paris, BFA, UMR 8251, CNRS, Paris, France (Q.N., J.B., W.Z., L.-C.B., R.L., F.B., J.-M.D., F.R.L.); Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao, China (X.X.); Université de Paris, BIGR, UMRS 1134, IN
  • Guidez F; Université de Paris, BFA, UMR 8251, CNRS, Paris, France (Q.N., J.B., W.Z., L.-C.B., R.L., F.B., J.-M.D., F.R.L.); Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao, China (X.X.); Université de Paris, BIGR, UMRS 1134, IN
  • Dupret JM; Université de Paris, BFA, UMR 8251, CNRS, Paris, France (Q.N., J.B., W.Z., L.-C.B., R.L., F.B., J.-M.D., F.R.L.); Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao, China (X.X.); Université de Paris, BIGR, UMRS 1134, IN
  • Rodrigues Lima F; Université de Paris, BFA, UMR 8251, CNRS, Paris, France (Q.N., J.B., W.Z., L.-C.B., R.L., F.B., J.-M.D., F.R.L.); Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao, China (X.X.); Université de Paris, BIGR, UMRS 1134, IN
Mol Pharmacol ; 96(2): 297-306, 2019 08.
Article en En | MEDLINE | ID: mdl-31221825
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Quinonas / Etopósido / Proteína Tirosina Fosfatasa no Receptora Tipo 2 Límite: Humans Idioma: En Revista: Mol Pharmacol Año: 2019 Tipo del documento: Article País de afiliación: India
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Quinonas / Etopósido / Proteína Tirosina Fosfatasa no Receptora Tipo 2 Límite: Humans Idioma: En Revista: Mol Pharmacol Año: 2019 Tipo del documento: Article País de afiliación: India