Intermediate metabolites of the pyrimidine metabolism pathway extend the lifespan of <i>C. elegans</i> through regulating reproductive signals.

Wan, Qin-Li; Meng, Xiao; Fu, Xiaodie; Chen, Bohui; Yang, Jing; Yang, Hengwen; Zhou, Qinghua

Intermediate metabolites of the pyrimidine metabolism pathway extend the lifespan of C. elegans through regulating reproductive signals.

Wan, Qin-Li; Meng, Xiao; Fu, Xiaodie; Chen, Bohui; Yang, Jing; Yang, Hengwen; Zhou, Qinghua.

Afiliación

Wan QL; The Center for Precision Medicine of First Affiliated Hospital, Biomedical Translational Research Institute, Jinan University, Guangzhou 510632, China.
Meng X; The Center for Precision Medicine of First Affiliated Hospital, Biomedical Translational Research Institute, Jinan University, Guangzhou 510632, China.
Fu X; The Center for Precision Medicine of First Affiliated Hospital, Biomedical Translational Research Institute, Jinan University, Guangzhou 510632, China.
Chen B; The Center for Precision Medicine of First Affiliated Hospital, Biomedical Translational Research Institute, Jinan University, Guangzhou 510632, China.
Yang J; The Center for Precision Medicine of First Affiliated Hospital, Biomedical Translational Research Institute, Jinan University, Guangzhou 510632, China.
Yang H; The Center for Precision Medicine of First Affiliated Hospital, Biomedical Translational Research Institute, Jinan University, Guangzhou 510632, China.
Zhou Q; The Center for Precision Medicine of First Affiliated Hospital, Biomedical Translational Research Institute, Jinan University, Guangzhou 510632, China.

Aging (Albany NY) ; 11(12): 3993-4010, 2019 06 21.

Article en En | MEDLINE | ID: mdl-31232697

Asunto(s)

Proteínas de Caenorhabditis elegans/metabolismo; Caenorhabditis elegans/fisiología; Longevidad/fisiología; Pirimidinas/metabolismo; Animales; Proteínas de Caenorhabditis elegans/genética; Regulación de la Expresión Génica/fisiología; Interferencia de ARN; ARN Mensajero/genética; ARN Mensajero/metabolismo; Reproducción

Palabras clave

Caenorhabditis elegans; longevity; pyrimidine metabolism; reproductive signals

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Pirimidinas / Caenorhabditis elegans / Proteínas de Caenorhabditis elegans / Longevidad Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Aging (Albany NY) Asunto de la revista: GERIATRIA Año: 2019 Tipo del documento: Article País de afiliación: China

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