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A T164S mutation in the dengue virus NS1 protein is associated with greater disease severity in mice.
Chan, Kitti Wing Ki; Watanabe, Satoru; Jin, Jocelyn Y; Pompon, Julien; Teng, Don; Alonso, Sylvie; Vijaykrishna, Dhanasekaran; Halstead, Scott B; Marzinek, Jan K; Bond, Peter J; Burla, Bo; Torta, Federico; Wenk, Markus R; Ooi, Eng Eong; Vasudevan, Subhash G.
Afiliación
  • Chan KWK; Program in Emerging Infectious Diseases, Duke-NUS Medical School, 8 College Road, Singapore 169857, Singapore.
  • Watanabe S; Department of Microbiology and Immunology, 5 Science Drive 2, Singapore 117545, Singapore.
  • Jin JY; Program in Emerging Infectious Diseases, Duke-NUS Medical School, 8 College Road, Singapore 169857, Singapore.
  • Pompon J; Program in Emerging Infectious Diseases, Duke-NUS Medical School, 8 College Road, Singapore 169857, Singapore.
  • Teng D; Program in Emerging Infectious Diseases, Duke-NUS Medical School, 8 College Road, Singapore 169857, Singapore.
  • Alonso S; MIVEGEC, UMR IRD 224-CNRS5290 Université de Montpellier, Montpellier, France.
  • Vijaykrishna D; Biomedicine Discovery Institute and Department of Microbiology, Monash University, Melbourne, Victoria 3800, Australia.
  • Halstead SB; Department of Microbiology and Immunology, 5 Science Drive 2, Singapore 117545, Singapore.
  • Marzinek JK; Immunology Programme, Life Science Institute, National University of Singapore, Singapore 117456, Singapore.
  • Bond PJ; Program in Emerging Infectious Diseases, Duke-NUS Medical School, 8 College Road, Singapore 169857, Singapore.
  • Burla B; Biomedicine Discovery Institute and Department of Microbiology, Monash University, Melbourne, Victoria 3800, Australia.
  • Torta F; Department of Preventive Medicine and Biometrics, Uniformed Services University of the Health Sciences, Bethesda, MD 20817, USA.
  • Wenk MR; Bioinformatics Institute (A*STAR), 30 Biopolis St., Singapore 138671, Singapore.
  • Ooi EE; Bioinformatics Institute (A*STAR), 30 Biopolis St., Singapore 138671, Singapore.
  • Vasudevan SG; Singapore Lipidomics Incubator (SLING), Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore.
Sci Transl Med ; 11(498)2019 06 26.
Article en En | MEDLINE | ID: mdl-31243154

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Índice de Severidad de la Enfermedad / Proteínas no Estructurales Virales / Dengue / Virus del Dengue / Mutación Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Animals Idioma: En Revista: Sci Transl Med Asunto de la revista: CIENCIA / MEDICINA Año: 2019 Tipo del documento: Article País de afiliación: Singapur

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Índice de Severidad de la Enfermedad / Proteínas no Estructurales Virales / Dengue / Virus del Dengue / Mutación Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Animals Idioma: En Revista: Sci Transl Med Asunto de la revista: CIENCIA / MEDICINA Año: 2019 Tipo del documento: Article País de afiliación: Singapur