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Effects of a High-fat Meal on the Pharmacokinetics of the VEGFR Inhibitor Fruquintinib: A Randomized Phase I Study in Healthy Subjects.
Qian, Hongjie; Fan, Songhua; Li, Ke; Sai, Yang; Su, Weiguo; Chen, Qian; Liu, Yun; Li, Tingting; Wang, Wei; Jia, Jingying; Yu, Chen; Liu, Yanmei.
Afiliación
  • Qian H; Laboratory of Immunology and Virology, Shanghai University of Traditional Chinese Medicine, Shanghai, China; Central Laboratory, Shanghai Xuhui Central Hospital, Zhongshan-Xuhui Hospital, Fudan University, Shanghai, China.
  • Fan S; Hutchison MediPharma Ltd, Shanghai, China.
  • Li K; Hutchison MediPharma Ltd, Shanghai, China.
  • Sai Y; Hutchison MediPharma Ltd, Shanghai, China.
  • Su W; Hutchison MediPharma Ltd, Shanghai, China.
  • Chen Q; Central Laboratory, Shanghai Xuhui Central Hospital, Zhongshan-Xuhui Hospital, Fudan University, Shanghai, China.
  • Liu Y; Central Laboratory, Shanghai Xuhui Central Hospital, Zhongshan-Xuhui Hospital, Fudan University, Shanghai, China.
  • Li T; Central Laboratory, Shanghai Xuhui Central Hospital, Zhongshan-Xuhui Hospital, Fudan University, Shanghai, China.
  • Wang W; Department of Emergency, Shanghai Xuhui Central Hospital, Zhongshan-Xuhui Hospital, Fudan University, Shanghai, China.
  • Jia J; Central Laboratory, Shanghai Xuhui Central Hospital, Zhongshan-Xuhui Hospital, Fudan University, Shanghai, China.
  • Yu C; Central Laboratory, Shanghai Xuhui Central Hospital, Zhongshan-Xuhui Hospital, Fudan University, Shanghai, China.
  • Liu Y; Central Laboratory, Shanghai Xuhui Central Hospital, Zhongshan-Xuhui Hospital, Fudan University, Shanghai, China. Electronic address: ymliu@shxh-centerlab.com.
Clin Ther ; 41(8): 1537-1544, 2019 08.
Article en En | MEDLINE | ID: mdl-31272709
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Quinazolinas / Benzofuranos / Grasas de la Dieta / Interacciones Alimento-Droga / Receptores de Factores de Crecimiento Endotelial Vascular / Inhibidores de Proteínas Quinasas Tipo de estudio: Clinical_trials / Prognostic_studies Límite: Adolescent / Adult / Humans / Male / Middle aged Idioma: En Revista: Clin Ther Año: 2019 Tipo del documento: Article País de afiliación: China
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Quinazolinas / Benzofuranos / Grasas de la Dieta / Interacciones Alimento-Droga / Receptores de Factores de Crecimiento Endotelial Vascular / Inhibidores de Proteínas Quinasas Tipo de estudio: Clinical_trials / Prognostic_studies Límite: Adolescent / Adult / Humans / Male / Middle aged Idioma: En Revista: Clin Ther Año: 2019 Tipo del documento: Article País de afiliación: China