Shared Transcriptional Control of Innate Lymphoid Cell and Dendritic Cell Development.
Annu Rev Cell Dev Biol
; 35: 381-406, 2019 10 06.
Article
en En
| MEDLINE
| ID: mdl-31283378
ABSTRACT
Innate immunity and adaptive immunity consist of highly specialized immune lineages that depend on transcription factors for both function and development. In this review, we dissect the similarities between two innate lineages, innate lymphoid cells (ILCs) and dendritic cells (DCs), and an adaptive immune lineage, T cells. ILCs, DCs, and T cells make up four functional immune modules and interact in concert to produce a specified immune response. These three immune lineages also share transcriptional networks governing the development of each lineage, and we discuss the similarities between ILCs and DCs in this review.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Células Dendríticas
/
Linfocitos
/
Redes Reguladoras de Genes
/
Inmunidad Adaptativa
/
Inmunidad Innata
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Annu Rev Cell Dev Biol
Asunto de la revista:
BIOLOGIA
Año:
2019
Tipo del documento:
Article