Air pollution, lung function and COPD: results from the population-based UK Biobank study.
Eur Respir J
; 54(1)2019 07.
Article
en En
| MEDLINE
| ID: mdl-31285306
ABSTRACT
Ambient air pollution increases the risk of respiratory mortality, but evidence for impacts on lung function and chronic obstructive pulmonary disease (COPD) is less well established. The aim was to evaluate whether ambient air pollution is associated with lung function and COPD, and explore potential vulnerability factors.We used UK Biobank data on 303â887 individuals aged 40-69â
years, with complete covariate data and valid lung function measures. Cross-sectional analyses examined associations of land use regression-based estimates of particulate matter (particles with a 50% cut-off aerodynamic diameter of 2.5 and 10â
µm PM2.5 and PM10, respectively; and coarse particles with diameter between 2.5â
µm and 10â
µm PMcoarse) and nitrogen dioxide (NO2) concentrations with forced expiratory volume in 1â
s (FEV1), forced vital capacity (FVC), the FEV1/FVC ratio and COPD (FEV1/FVC
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Enfermedad Pulmonar Obstructiva Crónica
/
Contaminación del Aire
/
Exposición a Riesgos Ambientales
/
Material Particulado
/
Dióxido de Nitrógeno
Tipo de estudio:
Diagnostic_studies
/
Etiology_studies
/
Observational_studies
/
Prevalence_studies
/
Risk_factors_studies
Límite:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
País/Región como asunto:
Europa
Idioma:
En
Revista:
Eur Respir J
Año:
2019
Tipo del documento:
Article
País de afiliación:
Canadá