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Structure based design of selective SHP2 inhibitors by De novo design, synthesis and biological evaluation.
Liu, Wen-Shan; Jin, Wen-Yan; Zhou, Liang; Lu, Xing-Hua; Li, Wei-Ya; Ma, Ying; Wang, Run-Ling.
Afiliación
  • Liu WS; Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics (Theranostics), School of Pharmacy, Tianjin Medical University, No. 22 Qixiangtai Rd, Heping Dist, Tianjin, 300070, People's Republic of China.
  • Jin WY; Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics (Theranostics), School of Pharmacy, Tianjin Medical University, No. 22 Qixiangtai Rd, Heping Dist, Tianjin, 300070, People's Republic of China.
  • Zhou L; Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics (Theranostics), School of Pharmacy, Tianjin Medical University, No. 22 Qixiangtai Rd, Heping Dist, Tianjin, 300070, People's Republic of China.
  • Lu XH; Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics (Theranostics), School of Pharmacy, Tianjin Medical University, No. 22 Qixiangtai Rd, Heping Dist, Tianjin, 300070, People's Republic of China.
  • Li WY; Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics (Theranostics), School of Pharmacy, Tianjin Medical University, No. 22 Qixiangtai Rd, Heping Dist, Tianjin, 300070, People's Republic of China.
  • Ma Y; Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics (Theranostics), School of Pharmacy, Tianjin Medical University, No. 22 Qixiangtai Rd, Heping Dist, Tianjin, 300070, People's Republic of China. maying@tmu.edu.cn.
  • Wang RL; Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics (Theranostics), School of Pharmacy, Tianjin Medical University, No. 22 Qixiangtai Rd, Heping Dist, Tianjin, 300070, People's Republic of China. wangrunling@tmu.edu.cn.
J Comput Aided Mol Des ; 33(8): 759-774, 2019 08.
Article en En | MEDLINE | ID: mdl-31300938
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Inhibidores Enzimáticos / Proteína Tirosina Fosfatasa no Receptora Tipo 11 / Neoplasias Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: J Comput Aided Mol Des Asunto de la revista: BIOLOGIA MOLECULAR / ENGENHARIA BIOMEDICA Año: 2019 Tipo del documento: Article
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Inhibidores Enzimáticos / Proteína Tirosina Fosfatasa no Receptora Tipo 11 / Neoplasias Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: J Comput Aided Mol Des Asunto de la revista: BIOLOGIA MOLECULAR / ENGENHARIA BIOMEDICA Año: 2019 Tipo del documento: Article