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The new psychoactive substance 3-methylmethcathinone (3-MMC or metaphedrone) induces oxidative stress, apoptosis, and autophagy in primary rat hepatocytes at human-relevant concentrations.
Dias da Silva, Diana; Ferreira, Bárbara; Roque Bravo, Rita; Rebelo, Rita; Duarte de Almeida, Tomás; Valente, Maria João; Silva, João Pedro; Carvalho, Félix; Bastos, Maria de Lourdes; Carmo, Helena.
Afiliación
  • Dias da Silva D; UCIBIO, REQUIMTE, Laboratory of Toxicology, Department of Biological Sciences, Faculty of Pharmacy, University of Porto, Rua Jorge Viterbo Ferreira, 228, 4050-313, Porto, Portugal. diana.dds@gmail.com.
  • Ferreira B; UCIBIO, REQUIMTE, Laboratory of Toxicology, Department of Biological Sciences, Faculty of Pharmacy, University of Porto, Rua Jorge Viterbo Ferreira, 228, 4050-313, Porto, Portugal.
  • Roque Bravo R; UCIBIO, REQUIMTE, Laboratory of Toxicology, Department of Biological Sciences, Faculty of Pharmacy, University of Porto, Rua Jorge Viterbo Ferreira, 228, 4050-313, Porto, Portugal.
  • Rebelo R; UCIBIO, REQUIMTE, Laboratory of Toxicology, Department of Biological Sciences, Faculty of Pharmacy, University of Porto, Rua Jorge Viterbo Ferreira, 228, 4050-313, Porto, Portugal.
  • Duarte de Almeida T; UCIBIO, REQUIMTE, Laboratory of Toxicology, Department of Biological Sciences, Faculty of Pharmacy, University of Porto, Rua Jorge Viterbo Ferreira, 228, 4050-313, Porto, Portugal.
  • Valente MJ; UCIBIO, REQUIMTE, Laboratory of Biochemistry Department of Biological Sciences, Faculty of Pharmacy, University of Porto, Rua Jorge Viterbo Ferreira, 228, 4050-313, Porto, Portugal.
  • Silva JP; UCIBIO, REQUIMTE, Laboratory of Toxicology, Department of Biological Sciences, Faculty of Pharmacy, University of Porto, Rua Jorge Viterbo Ferreira, 228, 4050-313, Porto, Portugal.
  • Carvalho F; UCIBIO, REQUIMTE, Laboratory of Toxicology, Department of Biological Sciences, Faculty of Pharmacy, University of Porto, Rua Jorge Viterbo Ferreira, 228, 4050-313, Porto, Portugal.
  • Bastos ML; UCIBIO, REQUIMTE, Laboratory of Toxicology, Department of Biological Sciences, Faculty of Pharmacy, University of Porto, Rua Jorge Viterbo Ferreira, 228, 4050-313, Porto, Portugal.
  • Carmo H; UCIBIO, REQUIMTE, Laboratory of Toxicology, Department of Biological Sciences, Faculty of Pharmacy, University of Porto, Rua Jorge Viterbo Ferreira, 228, 4050-313, Porto, Portugal. helenacarmo@ff.up.pt.
Arch Toxicol ; 93(9): 2617-2634, 2019 09.
Article en En | MEDLINE | ID: mdl-31468101
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Psicotrópicos / Autofagia / Apoptosis / Estrés Oxidativo / Hepatocitos / Metanfetamina Tipo de estudio: Risk_factors_studies Límite: Animals / Humans / Male Idioma: En Revista: Arch Toxicol Año: 2019 Tipo del documento: Article País de afiliación: Portugal
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Psicotrópicos / Autofagia / Apoptosis / Estrés Oxidativo / Hepatocitos / Metanfetamina Tipo de estudio: Risk_factors_studies Límite: Animals / Humans / Male Idioma: En Revista: Arch Toxicol Año: 2019 Tipo del documento: Article País de afiliación: Portugal