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A region-based gene association study combined with a leave-one-out sensitivity analysis identifies SMG1 as a pancreatic cancer susceptibility gene.
Wong, Cavin; Chen, Fei; Alirezaie, Najmeh; Wang, Yifan; Cuggia, Adeline; Borgida, Ayelet; Holter, Spring; Lenko, Tatiana; Domecq, Celine; Petersen, Gloria M; Syngal, Sapna; Brand, Randall; Rustgi, Anil K; Cote, Michele L; Stoffel, Elena; Olson, Sara H; Roberts, Nicholas J; Akbari, Mohammad R; Majewski, Jacek; Klein, Alison P; Greenwood, Celia M T; Gallinger, Steven; Zogopoulos, George.
Afiliación
  • Wong C; The Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada.
  • Chen F; The Goodman Cancer Research Centre of McGill University, Montreal, Quebec, Canada.
  • Alirezaie N; Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America.
  • Wang Y; McGill University and Genome Quebec Innovation Centre, Montreal, Quebec, Canada.
  • Cuggia A; The Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada.
  • Borgida A; The Goodman Cancer Research Centre of McGill University, Montreal, Quebec, Canada.
  • Holter S; The Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada.
  • Lenko T; The Goodman Cancer Research Centre of McGill University, Montreal, Quebec, Canada.
  • Domecq C; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada.
  • Petersen GM; The Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada.
  • Syngal S; The Goodman Cancer Research Centre of McGill University, Montreal, Quebec, Canada.
  • Brand R; The Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada.
  • Rustgi AK; The Goodman Cancer Research Centre of McGill University, Montreal, Quebec, Canada.
  • Stoffel E; Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, United States of America.
  • Olson SH; Division of Cancer Genetics and Prevention, Dana-Farber Cancer Institute, Gastroenterology Division, Brigham and Women's Hospital, Harvard Medical Schozol, Boston, Massachusetts, United States of America.
  • Roberts NJ; Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.
  • Akbari MR; Division of Gastroenterology, Departments of Medicine and Genetics, Pancreatic Cancer Translation Center of Excellence, Abramson Cancer Center, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America.
  • Majewski J; Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, Michigan, United States of America.
  • Klein AP; Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, United States of America.
  • Greenwood CMT; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America.
  • Gallinger S; Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland, United States of America.
  • Zogopoulos G; The Sol Goldman Pancreatic Cancer Research Center, Department of Pathology, Johns Hopkins University, Baltimore, Maryland, United States of America.
PLoS Genet ; 15(8): e1008344, 2019 08.
Article en En | MEDLINE | ID: mdl-31469826
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias Pancreáticas / Análisis de Secuencia de ADN / Estudios de Asociación Genética Tipo de estudio: Diagnostic_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: PLoS Genet Asunto de la revista: GENETICA Año: 2019 Tipo del documento: Article País de afiliación: Canadá
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias Pancreáticas / Análisis de Secuencia de ADN / Estudios de Asociación Genética Tipo de estudio: Diagnostic_studies / Prognostic_studies / Risk_factors_studies Límite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: PLoS Genet Asunto de la revista: GENETICA Año: 2019 Tipo del documento: Article País de afiliación: Canadá