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Comprehensive genomic profiling of glioblastoma tumors, BTICs, and xenografts reveals stability and adaptation to growth environments.
Shen, Yaoqing; Grisdale, Cameron J; Islam, Sumaiya A; Bose, Pinaki; Lever, Jake; Zhao, Eric Y; Grinshtein, Natalie; Ma, Yussanne; Mungall, Andrew J; Moore, Richard A; Lun, Xueqing; Senger, Donna L; Robbins, Stephen M; Wang, Alice Yijun; MacIsaac, Julia L; Kobor, Michael S; Luchman, H Artee; Weiss, Samuel; Chan, Jennifer A; Blough, Michael D; Kaplan, David R; Cairncross, J Gregory; Marra, Marco A; Jones, Steven J M.
Afiliación
  • Shen Y; Canada's Michael Smith Genome Sciences Centre, British Columbia Cancer Agency, Vancouver, BC, Canada V5Z 4S6.
  • Grisdale CJ; Canada's Michael Smith Genome Sciences Centre, British Columbia Cancer Agency, Vancouver, BC, Canada V5Z 4S6.
  • Islam SA; Center for Molecular Medicine and Therapeutics, University of British Columbia, Vancouver, BC, Canada V5Z 4H4.
  • Bose P; Department of Medical Genetics, University of British Columbia, Vancouver, BC, Canada V6H 3N1.
  • Lever J; Department of Biochemistry & Molecular Biology, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada T2N 1N4.
  • Zhao EY; Department of Oncology, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada T2N 4N2.
  • Grinshtein N; Department of Surgery, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada T2N 2T9.
  • Ma Y; Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, AB, Canada T2N 4Z6.
  • Mungall AJ; Canada's Michael Smith Genome Sciences Centre, British Columbia Cancer Agency, Vancouver, BC, Canada V5Z 4S6.
  • Moore RA; Canada's Michael Smith Genome Sciences Centre, British Columbia Cancer Agency, Vancouver, BC, Canada V5Z 4S6.
  • Lun X; Program in Neurosciences and Mental Health, The Hospital for Sick Children, Toronto, ON, Canada M5G 1X8.
  • Senger DL; Canada's Michael Smith Genome Sciences Centre, British Columbia Cancer Agency, Vancouver, BC, Canada V5Z 4S6.
  • Robbins SM; Canada's Michael Smith Genome Sciences Centre, British Columbia Cancer Agency, Vancouver, BC, Canada V5Z 4S6.
  • Wang AY; Canada's Michael Smith Genome Sciences Centre, British Columbia Cancer Agency, Vancouver, BC, Canada V5Z 4S6.
  • MacIsaac JL; Department of Oncology, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada T2N 4N2.
  • Kobor MS; Clark H. Smith Brain Tumour Centre, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, AB, Canada T2N 4Z6.
  • Luchman HA; Department of Oncology, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada T2N 4N2.
  • Weiss S; Clark H. Smith Brain Tumour Centre, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, AB, Canada T2N 4Z6.
  • Chan JA; Department of Oncology, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada T2N 4N2.
  • Blough MD; Clark H. Smith Brain Tumour Centre, Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, AB, Canada T2N 4Z6.
  • Kaplan DR; Hotchkiss Brain Institute, University of Calgary, Calgary, AB, Canada T2N 4N1.
  • Cairncross JG; Center for Molecular Medicine and Therapeutics, University of British Columbia, Vancouver, BC, Canada V5Z 4H4.
  • Marra MA; Center for Molecular Medicine and Therapeutics, University of British Columbia, Vancouver, BC, Canada V5Z 4H4.
  • Jones SJM; Department of Medical Genetics, University of British Columbia, Vancouver, BC, Canada V6H 3N1.
Proc Natl Acad Sci U S A ; 116(38): 19098-19108, 2019 09 17.
Article en En | MEDLINE | ID: mdl-31471491
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Células Madre Neoplásicas / Neoplasias Encefálicas / Biomarcadores de Tumor / Regulación Neoplásica de la Expresión Génica / Glioblastoma / Genómica / Microambiente Tumoral Tipo de estudio: Observational_studies / Prognostic_studies Límite: Adult / Aged / Aged80 / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2019 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Células Madre Neoplásicas / Neoplasias Encefálicas / Biomarcadores de Tumor / Regulación Neoplásica de la Expresión Génica / Glioblastoma / Genómica / Microambiente Tumoral Tipo de estudio: Observational_studies / Prognostic_studies Límite: Adult / Aged / Aged80 / Animals / Female / Humans / Male / Middle aged Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2019 Tipo del documento: Article