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Flow stimulates drug transport in a human kidney proximal tubule-on-a-chip independent of primary cilia.
Vriend, Jelle; Peters, Janny G P; Nieskens, Tom T G; Skovronová, Renata; Blaimschein, Nina; Schmidts, Miriam; Roepman, Ronald; Schirris, Tom J J; Russel, Frans G M; Masereeuw, Rosalinde; Wilmer, Martijn J.
Afiliación
  • Vriend J; Department of Pharmacology and Toxicology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands. Electronic address: jelle.vriend@radboudumc.nl.
  • Peters JGP; Department of Pharmacology and Toxicology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.
  • Nieskens TTG; Department of Pharmacology and Toxicology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.
  • Skovronová R; Department of Pharmacology and Toxicology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.
  • Blaimschein N; Department of Pharmacology and Toxicology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.
  • Schmidts M; Department of Human Genetics, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands; Center for Pediatrics and Adolescent Medicine, University Hospital Freiburg, Freiburg University Faculty of Medicine, Freiburg, Germany.
  • Roepman R; Department of Human Genetics, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.
  • Schirris TJJ; Department of Pharmacology and Toxicology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands; Centre for Systems Biology and Bioenergetics, Radboud Center for Mitochondrial Medicine, Radboud University Medical Center, The Netherlands.
  • Russel FGM; Department of Pharmacology and Toxicology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands; Centre for Systems Biology and Bioenergetics, Radboud Center for Mitochondrial Medicine, Radboud University Medical Center, The Netherlands.
  • Masereeuw R; Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht, The Netherlands.
  • Wilmer MJ; Department of Pharmacology and Toxicology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.
Biochim Biophys Acta Gen Subj ; 1864(1): 129433, 2020 01.
Article en En | MEDLINE | ID: mdl-31520681
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Cilios / Dispositivos Laboratorio en un Chip / Lesión Renal Aguda / Túbulos Renales Proximales Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Biochim Biophys Acta Gen Subj Año: 2020 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Cilios / Dispositivos Laboratorio en un Chip / Lesión Renal Aguda / Túbulos Renales Proximales Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Biochim Biophys Acta Gen Subj Año: 2020 Tipo del documento: Article