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CRISPR/Cas9-based editing of a sensitive transcriptional regulatory element to achieve cell type-specific knockdown of the NEMO scaffold protein.
Babaei, Milad; Liu, Yuekun; Wuerzberger-Davis, Shelly M; McCaslin, Ethan Z; DiRusso, Christopher J; Yeo, Alan T; Kagermazova, Larisa; Miyamoto, Shigeki; Gilmore, Thomas D.
Afiliación
  • Babaei M; Department of Biology, Boston University, Boston, Massachusetts, United States of America.
  • Liu Y; Department of Biology, Boston University, Boston, Massachusetts, United States of America.
  • Wuerzberger-Davis SM; Department of Oncology, McArdle Laboratory for Cancer Research, University of Wisconsin Carbone Cancer Center, University of Wisconsin, Madison, Wisconsin, United States of America.
  • McCaslin EZ; Department of Biology, Boston University, Boston, Massachusetts, United States of America.
  • DiRusso CJ; Department of Biology, Boston University, Boston, Massachusetts, United States of America.
  • Yeo AT; Department of Biology, Boston University, Boston, Massachusetts, United States of America.
  • Kagermazova L; Department of Biology, Boston University, Boston, Massachusetts, United States of America.
  • Miyamoto S; Department of Oncology, McArdle Laboratory for Cancer Research, University of Wisconsin Carbone Cancer Center, University of Wisconsin, Madison, Wisconsin, United States of America.
  • Gilmore TD; Department of Biology, Boston University, Boston, Massachusetts, United States of America.
PLoS One ; 14(9): e0222588, 2019.
Article en En | MEDLINE | ID: mdl-31553754
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Quinasa I-kappa B / Elementos Reguladores de la Transcripción / Técnicas de Silenciamiento del Gen / Edición Génica Tipo de estudio: Diagnostic_studies Límite: Humans Idioma: En Revista: PLoS One Asunto de la revista: CIENCIA / MEDICINA Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Quinasa I-kappa B / Elementos Reguladores de la Transcripción / Técnicas de Silenciamiento del Gen / Edición Génica Tipo de estudio: Diagnostic_studies Límite: Humans Idioma: En Revista: PLoS One Asunto de la revista: CIENCIA / MEDICINA Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos