Aniridia and Axenfeld-Rieger Syndrome: Clinical presentations, molecular genetics and current/emerging therapies.
Exp Eye Res
; 189: 107815, 2019 12.
Article
en En
| MEDLINE
| ID: mdl-31560925
ABSTRACT
Aniridia and Axenfeld-Rieger Syndrome are related, human ocular disorders that are typically inherited in an autosomal dominant manner. Both result from incorrect development of the eye and have, as their most serious consequences, elevated risk to develop the blinding condition glaucoma. This review will focus on describing the clinical presentations of Aniridia and Axenfeld-Rieger Syndrome as well as the molecular genetics and current and emerging therapies used to treat patients.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Anomalías Múltiples
/
Aniridia
/
Enfermedades Hereditarias del Ojo
/
Anomalías del Ojo
/
Proteínas de Homeodominio
/
Segmento Anterior del Ojo
Tipo de estudio:
Diagnostic_studies
Límite:
Humans
Idioma:
En
Revista:
Exp Eye Res
Año:
2019
Tipo del documento:
Article
País de afiliación:
Canadá