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Amplification of the Mutation-Carrying BRCA2 Allele Promotes RAD51 Loading and PARP Inhibitor Resistance in the Absence of Reversion Mutations.
Park, Pyoung Hwa; Yamamoto, Tomomi M; Li, Hua; Alcivar, Allen L; Xia, Bing; Wang, Yifan; Bernhardy, Andrea J; Turner, Kristen M; Kossenkov, Andrew V; Watson, Zachary L; Behbakht, Kian; Casadei, Silvia; Swisher, Elizabeth M; Mischel, Paul S; Johnson, Neil; Bitler, Benjamin G.
Afiliación
  • Park PH; Gene Expression and Regulation Program, The Wistar Institute, Philadelphia, Pennsylvania.
  • Yamamoto TM; Division of Reproductive Sciences, The University of Colorado, Aurora, Colorado.
  • Li H; Gene Expression and Regulation Program, The Wistar Institute, Philadelphia, Pennsylvania.
  • Alcivar AL; Department of Radiation Oncology, The Cancer Institute of New Jersey, Rutgers University, New Brunswick, New Jersey.
  • Xia B; Department of Radiation Oncology, The Cancer Institute of New Jersey, Rutgers University, New Brunswick, New Jersey.
  • Wang Y; Molecular Therapeutics Program, Fox Chase Cancer Center, Philadelphia, Pennsylvania.
  • Bernhardy AJ; Molecular Therapeutics Program, Fox Chase Cancer Center, Philadelphia, Pennsylvania.
  • Turner KM; Moores Cancer Center, University of California at San Diego, La Jolla, California.
  • Kossenkov AV; Gene Expression and Regulation Program, The Wistar Institute, Philadelphia, Pennsylvania.
  • Watson ZL; Division of Reproductive Sciences, The University of Colorado, Aurora, Colorado.
  • Behbakht K; Division of Gynecologic Oncology, The University of Colorado, Aurora, Colorado.
  • Casadei S; Department of Ob/Gyn, University of Washington, Seattle, Washington.
  • Swisher EM; Department of Ob/Gyn, University of Washington, Seattle, Washington.
  • Mischel PS; Moores Cancer Center, University of California at San Diego, La Jolla, California.
  • Johnson N; Molecular Therapeutics Program, Fox Chase Cancer Center, Philadelphia, Pennsylvania.
  • Bitler BG; Division of Reproductive Sciences, The University of Colorado, Aurora, Colorado. Benjamin.bitler@cuanschutz.edu.
Mol Cancer Ther ; 19(2): 602-613, 2020 02.
Article en En | MEDLINE | ID: mdl-31575654
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias de la Mama / Resistencia a Antineoplásicos / Proteína BRCA2 / Recombinasa Rad51 / Inhibidores de Poli(ADP-Ribosa) Polimerasas Límite: Female / Humans Idioma: En Revista: Mol Cancer Ther Asunto de la revista: ANTINEOPLASICOS Año: 2020 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias de la Mama / Resistencia a Antineoplásicos / Proteína BRCA2 / Recombinasa Rad51 / Inhibidores de Poli(ADP-Ribosa) Polimerasas Límite: Female / Humans Idioma: En Revista: Mol Cancer Ther Asunto de la revista: ANTINEOPLASICOS Año: 2020 Tipo del documento: Article