Isolation of T-cell tropic HTLV-III-like retrovirus from macaques.
Science
; 228(4704): 1201-4, 1985 Jun 07.
Article
en En
| MEDLINE
| ID: mdl-3159089
ABSTRACT
The isolation of a T-cell tropic retrovirus from three immunodeficient macaques and one macaque with lymphoma is described. The morphology, growth characteristics, and antigenic properties of this virus indicate that it is related to the causative agent of acquired immune deficiency syndrome in humans (HTLV-III or LAV). This virus is referred to as simian T-lymphotropic virus type III (STLV-III) of macaques. The existence of a cytopathic, T-cell tropic virus resembling HTLV-III in monkeys may facilitate study of disease induction and vaccine development in an animal model.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Retroviridae
/
Linfocitos T
/
Síndrome de Inmunodeficiencia Adquirida
/
Macaca
/
Macaca mulatta
/
Enfermedades de los Monos
Tipo de estudio:
Prognostic_studies
Límite:
Animals
Idioma:
En
Revista:
Science
Año:
1985
Tipo del documento:
Article