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Annotations capturing cell type-specific TF binding explain a large fraction of disease heritability.
van de Geijn, Bryce; Finucane, Hilary; Gazal, Steven; Hormozdiari, Farhad; Amariuta, Tiffany; Liu, Xuanyao; Gusev, Alexander; Loh, Po-Ru; Reshef, Yakir; Kichaev, Gleb; Raychauduri, Soumya; Price, Alkes L.
Afiliación
  • van de Geijn B; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston 02115, MA, USA.
  • Finucane H; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.
  • Gazal S; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston 02115, MA, USA.
  • Hormozdiari F; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston 02115, MA, USA.
  • Amariuta T; Center for Data Sciences, Harvard Medical School, Boston, MA 02215, USA.
  • Liu X; Divisions of Genetics, Rheumatology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02215, USA.
  • Gusev A; Department of Biomedical Informatics, Harvard Medical School, Boston, MA 02215, USA.
  • Loh PR; Graduate School of Arts and Sciences, Harvard University, Boston, MA 02215, USA.
  • Reshef Y; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston 02115, MA, USA.
  • Kichaev G; Dana Farber Cancer Institute, Boston, MA 02215, USA.
  • Raychauduri S; Brigham and Women's Hospital, Boston, MA 02215, USA.
  • Price AL; Department of Computer Science, Harvard University, Cambridge, MA 02138, USA.
Hum Mol Genet ; 29(7): 1057-1067, 2020 05 08.
Article en En | MEDLINE | ID: mdl-31595288

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Factores de Transcripción / Cromatina / Anotación de Secuencia Molecular / Enfermedades Genéticas Congénitas Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Hum Mol Genet Asunto de la revista: BIOLOGIA MOLECULAR / GENETICA MEDICA Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Factores de Transcripción / Cromatina / Anotación de Secuencia Molecular / Enfermedades Genéticas Congénitas Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Hum Mol Genet Asunto de la revista: BIOLOGIA MOLECULAR / GENETICA MEDICA Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos