VDJbase: an adaptive immune receptor genotype and haplotype database.
Nucleic Acids Res
; 48(D1): D1051-D1056, 2020 01 08.
Article
en En
| MEDLINE
| ID: mdl-31602484
ABSTRACT
VDJbase is a publicly available database that offers easy searching of data describing the complete sets of gene sequences (genotypes and haplotypes) inferred from adaptive immune receptor repertoire sequencing datasets. VDJbase is designed to act as a resource that will allow the scientific community to explore the genetic variability of the immunoglobulin (Ig) and T cell receptor (TR) gene loci. It can also assist in the investigation of Ig- and TR-related genetic predispositions to diseases. Our database includes web-based query and online tools to assist in visualization and analysis of the genotype and haplotype data. It enables users to detect those alleles and genes that are significantly over-represented in a particular population, in terms of genotype, haplotype and gene expression. The database website can be freely accessed at https//www.vdjbase.org/, and no login is required. The data and code use creative common licenses and are freely downloadable from https//bitbucket.org/account/user/yaarilab/projects/GPHP.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Haplotipos
/
Receptores Inmunológicos
/
Biología Computacional
/
Bases de Datos Genéticas
/
Recombinación V(D)J
/
Genotipo
Límite:
Humans
Idioma:
En
Revista:
Nucleic Acids Res
Año:
2020
Tipo del documento:
Article
País de afiliación:
Israel