The link between periodontitis and erectile dysfunction: a review.

Introduction Consistent evidence has shown that periodontitis can be considered a risk factor for the development of vascular complications such as myocardial infarction and cerebrovascular accident. The majority of cases of erectile dysfunction (ED) are considered to result from the complication of vascular impairments. Therefore, it is conceivable to hypothesise that periodontitis can also be associated with ED.Aims To determine whether a possible link between periodontitis and ED exists by reviewing and presenting the current available evidence.Methods Current, up to June 2018, case-control studies, randomised controlled trials (RCT) and meta-analyses were reviewed.Results Nine case-control studies and three meta-analyses found significant positive associations between these two conditions, with odds ratios ranging from 1.53 to 5.94. Furthermore, one RCT found a significant improvement in subjective measurements of ED in patients treated for periodontitis.Conclusions The current associations must be interpreted with caution because of the considerable heterogeneity of the cross-sectional investigations and the short-term character of the only RCT included. Nevertheless, the preliminary results can be taken into consideration for the general physician or the specialist in the motivation of the male patient to visit dental professionals and, if indicated, treated for periodontitis, which may help in managing the vasculogenic form of impotence.