Embryonic Fundulus heteroclitus responses to sediment extracts from differentially contaminated sites in the Elizabeth River, VA.
Ecotoxicology
; 28(9): 1126-1135, 2019 Nov.
Article
en En
| MEDLINE
| ID: mdl-31620948
ABSTRACT
Sites along the Elizabeth River are contaminated with polycyclic aromatic hydrocarbons (PAHs) from historical creosote production and other industrial processes. Previous studies have demonstrated that Atlantic killifish collected from sites throughout the Elizabeth River display resistance to the teratogenic effects of PAH-exposure in a manner commensurate with sediment PAH concentrations. The current study characterized various chemical pollutants in sediment and investigated the effects of aqueous sediment extracts from sites along the Elizabeth River to the cardiac development of Atlantic killifish embryos from fish collected from an uncontaminated reference site. Embryonic cardiac deformities were more prevalent after exposure to extracts from sites with high PAH loads. However, activation of cytochrome P4501A, a gene up-regulated by PAH-induction of the aryl hydrocarbon receptor and measured using an in ovo EROD assay, did not consistently increase with PAH concentrations. This work further characterizes sediments in the Elizabeth River, as well as provides insight into the evolutionary pressures at each ER site.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Hidrocarburos Policíclicos Aromáticos
/
Contaminantes Químicos del Agua
/
Sedimentos Geológicos
/
Fundulidae
Límite:
Animals
País/Región como asunto:
America do norte
Idioma:
En
Revista:
Ecotoxicology
Asunto de la revista:
SAUDE AMBIENTAL
/
TOXICOLOGIA
Año:
2019
Tipo del documento:
Article
País de afiliación:
Estados Unidos