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The SINE Compound KPT-350 Blocks Dystrophic Pathologies in DMD Zebrafish and Mice.
Hightower, Rylie M; Reid, Andrea L; Gibbs, Devin E; Wang, Yimin; Widrick, Jeffrey J; Kunkel, Louis M; Kastenschmidt, Jenna M; Villalta, S Armando; van Groen, Thomas; Chang, Hua; Gornisiewicz, Savanna; Landesman, Yosef; Tamir, Sharon; Alexander, Matthew S.
Afiliación
  • Hightower RM; Department of Pediatrics, Division of Neurology, University of Alabama at Birmingham and Children's of Alabama, Birmingham, AL 35294, USA; UAB Center for Exercise Medicine (UCEM), Birmingham, AL 35294, USA.
  • Reid AL; Department of Pediatrics, Division of Neurology, University of Alabama at Birmingham and Children's of Alabama, Birmingham, AL 35294, USA.
  • Gibbs DE; Division of Genetics and Genomics at Boston Children's Hospital, Boston, MA 02115, USA.
  • Wang Y; Department of Pediatrics, Division of Neurology, University of Alabama at Birmingham and Children's of Alabama, Birmingham, AL 35294, USA.
  • Widrick JJ; Division of Genetics and Genomics at Boston Children's Hospital, Boston, MA 02115, USA.
  • Kunkel LM; Division of Genetics and Genomics at Boston Children's Hospital, Boston, MA 02115, USA; Department of Genetics at Harvard Medical School, Boston, MA 02115, USA; Harvard Stem Cell Institute, Cambridge, MA 02138, USA; The Manton Center for Orphan Disease Research at Boston Children's Hospital, Boston,
  • Kastenschmidt JM; Department of Physiology and Biophysics, University of California-Irvine, Irvine, CA 92697, USA; Institute for Immunology, University of California-Irvine, Irvine, CA 92697, USA.
  • Villalta SA; Department of Physiology and Biophysics, University of California-Irvine, Irvine, CA 92697, USA; Institute for Immunology, University of California-Irvine, Irvine, CA 92697, USA.
  • van Groen T; Department of Cell, Developmental, and Integrative Biology, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
  • Chang H; Karyopharm Therapeutics, Newton, MA 02459, USA.
  • Gornisiewicz S; Karyopharm Therapeutics, Newton, MA 02459, USA.
  • Landesman Y; Karyopharm Therapeutics, Newton, MA 02459, USA.
  • Tamir S; Karyopharm Therapeutics, Newton, MA 02459, USA.
  • Alexander MS; Department of Pediatrics, Division of Neurology, University of Alabama at Birmingham and Children's of Alabama, Birmingham, AL 35294, USA; UAB Center for Exercise Medicine (UCEM), Birmingham, AL 35294, USA; Department of Genetics at the University of Alabama at Birmingham, Birmingham, AL 35294, USA;
Mol Ther ; 28(1): 189-201, 2020 01 08.
Article en En | MEDLINE | ID: mdl-31628052
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Pez Cebra / Receptores Citoplasmáticos y Nucleares / Distrofia Muscular de Duchenne / Transporte Activo de Núcleo Celular / Carioferinas Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Mol Ther Asunto de la revista: BIOLOGIA MOLECULAR / TERAPEUTICA Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Pez Cebra / Receptores Citoplasmáticos y Nucleares / Distrofia Muscular de Duchenne / Transporte Activo de Núcleo Celular / Carioferinas Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Mol Ther Asunto de la revista: BIOLOGIA MOLECULAR / TERAPEUTICA Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos