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BRCA1 mislocalization leads to aberrant DNA damage response in heterozygous ABRAXAS1 mutation carrier cells.
Bose, Muthiah; Sachsenweger, Juliane; Laurila, Niina; Parplys, Ann Christin; Willmann, Jonas; Jungwirth, Johannes; Groth, Marco; Rapakko, Katrin; Nieminen, Pentti; Friedl, Thomas W P; Heiserich, Lisa; Meyer, Felix; Tuppurainen, Hanna; Peltoketo, Hellevi; Nevanlinna, Heli; Pylkäs, Katri; Borgmann, Kerstin; Wiesmüller, Lisa; Winqvist, Robert; Pospiech, Helmut.
Afiliación
  • Bose M; Laboratory of Cancer Genetics and Tumor Biology, Cancer and Translational Medicine Research Unit, Biocenter Oulu, University of Oulu and NordLab Oulu, 90220 Oulu, Finland.
  • Sachsenweger J; Laboratory of Cancer Genetics and Tumor Biology, Cancer and Translational Medicine Research Unit, Biocenter Oulu, University of Oulu and NordLab Oulu, 90220 Oulu, Finland.
  • Laurila N; Department of Obstetrics and Gynecology, Ulm University, 89075 Ulm, Germany.
  • Parplys AC; Laboratory of Cancer Genetics and Tumor Biology, Cancer and Translational Medicine Research Unit, Biocenter Oulu, University of Oulu and NordLab Oulu, 90220 Oulu, Finland.
  • Willmann J; Laboratory of Radiobiology and Experimental Radiooncology, University Cancer Center Hamburg (UCCH), University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
  • Jungwirth J; Laboratory of Radiobiology and Experimental Radiooncology, University Cancer Center Hamburg (UCCH), University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
  • Groth M; Project group Biochemistry, Leibniz Institute on Aging - Fritz Lipmann Institute, 07745 Jena, Germany.
  • Rapakko K; Core Facility DNA Sequencing, Leibniz Institute on Aging-Fritz Lipmann Institute, 07745 Jena, Germany.
  • Nieminen P; Laboratory of Genetics, Northern Finland Laboratory Centre NordLab Oulu, 90220 Oulu, Finland.
  • Friedl TWP; Department of Medical Informatics and Statistics, University of Oulu, 90220 Oulu, Finland.
  • Heiserich L; Department of Obstetrics and Gynecology, Ulm University, 89075 Ulm, Germany.
  • Meyer F; Medipan GmbH, 15827 Dahlewitz/Berlin, Germany.
  • Tuppurainen H; Laboratory of Radiobiology and Experimental Radiooncology, University Cancer Center Hamburg (UCCH), University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
  • Peltoketo H; Laboratory of Cancer Genetics and Tumor Biology, Cancer and Translational Medicine Research Unit, Biocenter Oulu, University of Oulu and NordLab Oulu, 90220 Oulu, Finland.
  • Nevanlinna H; Laboratory of Cancer Genetics and Tumor Biology, Cancer and Translational Medicine Research Unit, Biocenter Oulu, University of Oulu and NordLab Oulu, 90220 Oulu, Finland.
  • Pylkäs K; Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Central Hospital, Biomedicum Helsinki, 00029 Helsinki, Finland.
  • Borgmann K; Laboratory of Cancer Genetics and Tumor Biology, Cancer and Translational Medicine Research Unit, Biocenter Oulu, University of Oulu and NordLab Oulu, 90220 Oulu, Finland.
  • Wiesmüller L; Laboratory of Radiobiology and Experimental Radiooncology, University Cancer Center Hamburg (UCCH), University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
  • Winqvist R; Department of Obstetrics and Gynecology, Ulm University, 89075 Ulm, Germany.
  • Pospiech H; Laboratory of Cancer Genetics and Tumor Biology, Cancer and Translational Medicine Research Unit, Biocenter Oulu, University of Oulu and NordLab Oulu, 90220 Oulu, Finland.
Hum Mol Genet ; 28(24): 4148-4160, 2019 12 15.
Article en En | MEDLINE | ID: mdl-31630195
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias de la Mama / Proteínas Portadoras / Mutación de Línea Germinal / Proteína BRCA1 / Reparación del ADN / Roturas del ADN de Doble Cadena Límite: Adult / Female / Humans Idioma: En Revista: Hum Mol Genet Asunto de la revista: BIOLOGIA MOLECULAR / GENETICA MEDICA Año: 2019 Tipo del documento: Article País de afiliación: Finlandia
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Neoplasias de la Mama / Proteínas Portadoras / Mutación de Línea Germinal / Proteína BRCA1 / Reparación del ADN / Roturas del ADN de Doble Cadena Límite: Adult / Female / Humans Idioma: En Revista: Hum Mol Genet Asunto de la revista: BIOLOGIA MOLECULAR / GENETICA MEDICA Año: 2019 Tipo del documento: Article País de afiliación: Finlandia