Circular RNA LARP4 correlates with decreased Enneking stage, better histological response, and prolonged survival profiles, and it elevates chemosensitivity to cisplatin and doxorubicin via sponging microRNA-424 in osteosarcoma.

Hu, Yuhang; Gu, Jiaao; Shen, Hongtao; Shao, Tuo; Li, Song; Wang, Wei; Yu, Zhange

Hu, Yuhang; Gu, Jiaao; Shen, Hongtao; Shao, Tuo; Li, Song; Wang, Wei; Yu, Zhange.

Afiliación

Hu Y; Department of Orthopedics, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Gu J; Department of Orthopedics, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Shen H; Department of Orthopedics, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Shao T; Department of Orthopedics, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Li S; Department of Orthopedics, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Wang W; Department of Orthopedics, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Yu Z; Department of Orthopedics, The First Affiliated Hospital of Harbin Medical University, Harbin, China.

J Clin Lab Anal ; 34(2): e23045, 2020 Feb.

Article en En | MEDLINE | ID: mdl-31642110

Asunto(s)

Autoantígenos/genética; Neoplasias Óseas/tratamiento farmacológico; Resistencia a Antineoplásicos/genética; MicroARNs/genética; Osteosarcoma/tratamiento farmacológico; ARN Circular/genética; Ribonucleoproteínas/genética; Adolescente; Adulto; Antineoplásicos/farmacología; Neoplasias Óseas/genética; Neoplasias Óseas/mortalidad; Neoplasias Óseas/patología; Línea Celular Tumoral; Niño; Cisplatino/farmacología; Doxorrubicina/farmacología; Resistencia a Antineoplásicos/efectos de los fármacos; Femenino; Regulación Neoplásica de la Expresión Génica; Humanos; Masculino; Osteosarcoma/genética; Osteosarcoma/mortalidad; Osteosarcoma/patología; Tasa de Supervivencia; Adulto Joven; Antígeno SS-B

Palabras clave

Enneking stage; chemosensitivity; circ-LARP4; osteosarcoma; survival profile

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Ribonucleoproteínas / Autoantígenos / Neoplasias Óseas / Osteosarcoma / Resistencia a Antineoplásicos / MicroARNs / ARN Circular Límite: Adolescent / Adult / Child / Female / Humans / Male Idioma: En Revista: J Clin Lab Anal Asunto de la revista: TECNICAS E PROCEDIMENTOS DE LABORATORIO Año: 2020 Tipo del documento: Article País de afiliación: China

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