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Mimicking the human environment in mice reveals that inhibiting biotin biosynthesis is effective against antibiotic-resistant pathogens.
Carfrae, Lindsey A; MacNair, Craig R; Brown, Christopher M; Tsai, Caressa N; Weber, Brent S; Zlitni, Soumaya; Rao, Vishwas N; Chun, Joshua; Junop, Murray S; Coombes, Brian K; Brown, Eric D.
Afiliación
  • Carfrae LA; Michael G. DeGroote Institute for Infectious Disease Research, Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada.
  • MacNair CR; Michael G. DeGroote Institute for Infectious Disease Research, Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada.
  • Brown CM; Michael G. DeGroote Institute for Infectious Disease Research, Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada.
  • Tsai CN; Michael G. DeGroote Institute for Infectious Disease Research, Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada.
  • Weber BS; Michael G. DeGroote Institute for Infectious Disease Research, Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada.
  • Zlitni S; Michael G. DeGroote Institute for Infectious Disease Research, Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada.
  • Rao VN; Department of Medicine, Division of Hematology, Stanford University, Stanford, CA, USA.
  • Chun J; Michael G. DeGroote Institute for Infectious Disease Research, Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada.
  • Junop MS; Michael G. DeGroote Institute for Infectious Disease Research, Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada.
  • Coombes BK; Department of Biochemistry, Western University, London, Ontario, Canada.
  • Brown ED; Michael G. DeGroote Institute for Infectious Disease Research, Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada.
Nat Microbiol ; 5(1): 93-101, 2020 01.
Article en En | MEDLINE | ID: mdl-31659298
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Bacterias / Infecciones Bacterianas / Biotina / Farmacorresistencia Bacteriana / Antibacterianos Límite: Animals / Humans Idioma: En Revista: Nat Microbiol Año: 2020 Tipo del documento: Article País de afiliación: Canadá
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Bacterias / Infecciones Bacterianas / Biotina / Farmacorresistencia Bacteriana / Antibacterianos Límite: Animals / Humans Idioma: En Revista: Nat Microbiol Año: 2020 Tipo del documento: Article País de afiliación: Canadá