Dasymaschalolactams A-E, Aristolactams from a Twig Extract of Dasymaschalon dasymaschalum.
J Nat Prod
; 82(11): 3176-3180, 2019 11 22.
Article
en En
| MEDLINE
| ID: mdl-31661271
ABSTRACT
Five new aristolactam alkaloids (1-5), dasymaschalolactams A-E, and the first isolation of dasymaschalolactone (17) as a natural product, together with 19 known compounds (6-16 and 18-25) were isolated from the twig extract of Dasymaschalon dasymaschalum. Their structures were elucidated by spectroscopic methods as well as comparisons made from the literature. Compounds 20 and 21 showed α-glucosidase inhibitory activities with IC50 values of 4.5 and 24.7 µM, respectively.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Annonaceae
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Inhibidores Enzimáticos
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Inhibidores de Glicósido Hidrolasas
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Hipoglucemiantes
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Lactamas
Idioma:
En
Revista:
J Nat Prod
Año:
2019
Tipo del documento:
Article