Bidirectional Regulatory Mechanisms of Jaceosidin on Mitochondria Function: Protective Effects of the Permeability Transition and Damage of Membrane Functions.

Fu, Wen-Rong; Chen, Ji-Lei; Li, Xue-Yi; Dong, Jia-Xin; Liu, Yi

Fu, Wen-Rong; Chen, Ji-Lei; Li, Xue-Yi; Dong, Jia-Xin; Liu, Yi.

Afiliación

Fu WR; State Key Laboratory for the Chemistry and Molecular Engineering of Medicinal Resources, School of Chemistry and Pharmaceutical Sciences, Guangxi Normal University, Guilin, 541004, People's Republic of China.
Chen JL; State Key Laboratory of Virology & Key Laboratory of Analytical Chemistry for Biology and Medicine (MOE), College of Chemistry and Molecular Sciences, Wuhan University, Wuhan, 430072, People's Republic of China.
Li XY; State Key Laboratory for the Chemistry and Molecular Engineering of Medicinal Resources, School of Chemistry and Pharmaceutical Sciences, Guangxi Normal University, Guilin, 541004, People's Republic of China.
Dong JX; State Key Laboratory for the Chemistry and Molecular Engineering of Medicinal Resources, School of Chemistry and Pharmaceutical Sciences, Guangxi Normal University, Guilin, 541004, People's Republic of China. chemdjx@mailbox.gxnu.edu.cn.
Liu Y; State Key Laboratory of Virology & Key Laboratory of Analytical Chemistry for Biology and Medicine (MOE), College of Chemistry and Molecular Sciences, Wuhan University, Wuhan, 430072, People's Republic of China. yiliuchem@whu.edu.cn.

J Membr Biol ; 253(1): 25-35, 2020 02.

Article en En | MEDLINE | ID: mdl-31712855

Asunto(s)

Flavonoides/farmacología; Mitocondrias/efectos de los fármacos; Mitocondrias/metabolismo; Adenosina Trifosfato/metabolismo; Animales; Calcio/metabolismo; Transporte de Electrón/efectos de los fármacos; Flavonoides/química; Hidrógeno/metabolismo; Peroxidación de Lípido; Fluidez de la Membrana; Potencial de la Membrana Mitocondrial/efectos de los fármacos; Mitocondrias/ultraestructura; Mitocondrias Hepáticas/efectos de los fármacos; Mitocondrias Hepáticas/metabolismo; Membranas Mitocondriales/efectos de los fármacos; Membranas Mitocondriales/metabolismo; Estructura Molecular; Permeabilidad/efectos de los fármacos; Potasio/metabolismo; Ratas; Especies Reactivas de Oxígeno/metabolismo

Palabras clave

Bidirectional regulatory; Jaceosidin; Membrane function damage; Mitochondrial permeability transition; Protective effect

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Flavonoides / Mitocondrias Límite: Animals Idioma: En Revista: J Membr Biol Año: 2020 Tipo del documento: Article

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