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Exclusion of unsuitable CNS drug candidates based on their physicochemical properties and unbound fractions in biomatrices for brain microdialysis investigations.
Wang, Qianwen; Ren, Tianjing; Zhao, Jiajia; Wong, Chun-Ho; Chan, H Y Edwin; Zuo, Zhong.
Afiliación
  • Wang Q; School of Pharmacy, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong.
  • Ren T; School of Pharmacy, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong.
  • Zhao J; School of Pharmacy, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong.
  • Wong CH; School of Life Sciences, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong.
  • Chan HYE; School of Life Sciences, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong; Gerald Choa Neuroscience Centre, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong.
  • Zuo Z; School of Pharmacy, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong. Electronic address: joanzuo@cuhk.edu.hk.
J Pharm Biomed Anal ; 178: 112946, 2020 Jan 30.
Article en En | MEDLINE | ID: mdl-31727358
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Encéfalo / Fármacos del Sistema Nervioso Central Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: J Pharm Biomed Anal Año: 2020 Tipo del documento: Article País de afiliación: Hong Kong
Texto completo
Imprimir
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Encéfalo / Fármacos del Sistema Nervioso Central Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: J Pharm Biomed Anal Año: 2020 Tipo del documento: Article País de afiliación: Hong Kong