SIRT6 inhibits cholesterol crystal-induced vascular endothelial dysfunction via Nrf2 activation.

Jin, Zhen; Xiao, Yunfang; Yao, Feng; Wang, Bo; Zheng, Zihan; Gao, Hongqian; Lv, Xiaohan; Chen, Lifang; He, Yanhao; Wang, Weirong; Lin, Rong

Jin, Zhen; Xiao, Yunfang; Yao, Feng; Wang, Bo; Zheng, Zihan; Gao, Hongqian; Lv, Xiaohan; Chen, Lifang; He, Yanhao; Wang, Weirong; Lin, Rong.

Afiliación

Jin Z; Department of Pharmacology, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi, 710061, China.
Xiao Y; Department of Pharmacology, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi, 710061, China.
Yao F; School of Pharmacy, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi, 710061, China.
Wang B; Department of Pharmacology, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi, 710061, China.
Zheng Z; Department of Pharmacology, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi, 710061, China.
Gao H; School of Pharmacy, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi, 710061, China.
Lv X; School of Pharmacy, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi, 710061, China.
Chen L; Laboratory Animal Center, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi, 710061, China.
He Y; Department of Pharmacology, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi, 710061, China.
Wang W; Laboratory Animal Center, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi, 710061, China.
Lin R; Department of Pharmacology, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi, 710061, China. Electronic address: linrong@xjtu.redu.cn.

Exp Cell Res ; 387(1): 111744, 2020 02 01.

Article en En | MEDLINE | ID: mdl-31759967

Asunto(s)

Aterosclerosis/metabolismo; Colesterol/metabolismo; Endotelio Vascular/metabolismo; Factor 2 Relacionado con NF-E2/metabolismo; Sirtuinas/metabolismo; Animales; Células Cultivadas; Femenino; Células Endoteliales de la Vena Umbilical Humana; Humanos; Hiperlipidemias/metabolismo; Masculino; Ratones; Óxido Nítrico/metabolismo; Óxido Nítrico Sintasa de Tipo III/metabolismo

Palabras clave

Cholesterol crystals; Endothelial dysfunction; Nrf2; SIRT6; Vascular endothelium

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Endotelio Vascular / Colesterol / Sirtuinas / Aterosclerosis / Factor 2 Relacionado con NF-E2 Límite: Animals / Female / Humans / Male Idioma: En Revista: Exp Cell Res Año: 2020 Tipo del documento: Article País de afiliación: China

Texto completo

Imprimir

XML

PubMed Links

Buscar en Google