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Functional Enhancers Shape Extrachromosomal Oncogene Amplifications.
Morton, Andrew R; Dogan-Artun, Nergiz; Faber, Zachary J; MacLeod, Graham; Bartels, Cynthia F; Piazza, Megan S; Allan, Kevin C; Mack, Stephen C; Wang, Xiuxing; Gimple, Ryan C; Wu, Qiulian; Rubin, Brian P; Shetty, Shashirekha; Angers, Stephane; Dirks, Peter B; Sallari, Richard C; Lupien, Mathieu; Rich, Jeremy N; Scacheri, Peter C.
Afiliación
  • Morton AR; Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Case Comprehensive Cancer Center, Cleveland, OH 44106, USA.
  • Dogan-Artun N; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 1L7, Canada.
  • Faber ZJ; Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Case Comprehensive Cancer Center, Cleveland, OH 44106, USA.
  • MacLeod G; Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, ON M5S 3M2, Canada.
  • Bartels CF; Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Case Comprehensive Cancer Center, Cleveland, OH 44106, USA.
  • Piazza MS; Center for Human Genetics Laboratory, University Hospitals, Cleveland, OH 44106, USA.
  • Allan KC; Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Case Comprehensive Cancer Center, Cleveland, OH 44106, USA.
  • Mack SC; Department of Pediatrics, Division of Hematology and Oncology, Baylor College of Medicine, Texas Children's Hospital, Houston, TX 77030, USA.
  • Wang X; Department of Medicine, Division of Regenerative Medicine, University of California, San Diego, La Jolla, CA 92037, USA.
  • Gimple RC; Department of Medicine, Division of Regenerative Medicine, University of California, San Diego, La Jolla, CA 92037, USA; Department of Pathology, Case Western Reserve University, Cleveland, OH 44120, USA.
  • Wu Q; Department of Medicine, Division of Regenerative Medicine, University of California, San Diego, La Jolla, CA 92037, USA.
  • Rubin BP; Departments of Anatomic Pathology and Molecular Genetics, Cleveland Clinic, Lerner Research Institute and Taussig Cancer Center, Cleveland, OH 44195, USA.
  • Shetty S; Center for Human Genetics Laboratory, University Hospitals, Cleveland, OH 44106, USA.
  • Angers S; Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, ON M5S 3M2, Canada; Department of Biochemistry, Faculty of Medicine, University of Toronto, Toronto, ON M5G 0A4, Canada.
  • Dirks PB; Developmental and Stem Cell Biology Program and Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada; Ontario Institute for Cancer Research, Toronto, ON M5G 0A3, Canada.
  • Sallari RC; Axiotl Inc., Tucson, AZ 85701, USA.
  • Lupien M; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 1L7, Canada; Ontario Institute for Cancer Research, Toronto, ON M5G 0A3, Canada; Department of Medical Biophysics, University of Toronto, Toronto, ON M5S 1A8, Canada.
  • Rich JN; Department of Medicine, Division of Regenerative Medicine, University of California, San Diego, La Jolla, CA 92037, USA; Department of Neurosciences, University of California, San Diego, School of Medicine, La Jolla, CA 92037, USA. Electronic address: drjeremyrich@gmail.com.
  • Scacheri PC; Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Case Comprehensive Cancer Center, Cleveland, OH 44106, USA. Electronic address: pxs183@case.edu.
Cell ; 179(6): 1330-1341.e13, 2019 11 27.
Article en En | MEDLINE | ID: mdl-31761532
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Oncogenes / Amplificación de Genes / Cromosomas Humanos / Elementos de Facilitación Genéticos Límite: Humans Idioma: En Revista: Cell Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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PubMed Links
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Oncogenes / Amplificación de Genes / Cromosomas Humanos / Elementos de Facilitación Genéticos Límite: Humans Idioma: En Revista: Cell Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos