The steroid receptor coactivator 1 (SRC1) and 3 (SRC3) recruitment as a novel molecular initiating event of 4-n-nonylphenol in estrogen receptor &#945;-mediated pathways.

Ji, Xiaoya; Li, Na; Yang, Rong; Rao, Kaifeng; Ma, Mei; Wang, Zijian

The steroid receptor coactivator 1 (SRC1) and 3 (SRC3) recruitment as a novel molecular initiating event of 4-n-nonylphenol in estrogen receptor α-mediated pathways.

Ji, Xiaoya; Li, Na; Yang, Rong; Rao, Kaifeng; Ma, Mei; Wang, Zijian.

Afiliación

Ji X; Key Laboratory of Drinking Water Science and Technology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, 100085, China; College of Resources and Environment, University of Chinese Academy of Sciences, Beijing, 100049, China.
Li N; Key Laboratory of Drinking Water Science and Technology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, 100085, China; College of Resources and Environment, University of Chinese Academy of Sciences, Beijing, 100049, China.
Yang R; Beijing Water Quality Monitoring Center for South-to-North Water Diversion, Beijing, 100093, China.
Rao K; Key Laboratory of Drinking Water Science and Technology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, 100085, China.
Ma M; Key Laboratory of Drinking Water Science and Technology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, 100085, China; College of Resources and Environment, University of Chinese Academy of Sciences, Beijing, 100049, China. Electronic address: mamei@rcees.ac.cn
Wang Z; Key Laboratory of Drinking Water Science and Technology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, 100085, China.

Ecotoxicol Environ Saf ; 189: 109958, 2020 Feb.

Article en En | MEDLINE | ID: mdl-31767456

Asunto(s)

Contaminantes Ambientales/farmacología; Receptor alfa de Estrógeno/metabolismo; Estrógenos/farmacología; Coactivador 1 de Receptor Nuclear/metabolismo; Coactivador 3 de Receptor Nuclear/metabolismo; Fenoles/farmacología; Proliferación Celular/efectos de los fármacos; Humanos; Células MCF-7

Palabras clave

4-n-Nonylphenol; Estrogen receptor α (ERα); Estrogenic activity; Molecular initiating event (MIE); Steroid receptor coactivator (SRC)

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Fenoles / Receptor alfa de Estrógeno / Contaminantes Ambientales / Estrógenos / Coactivador 1 de Receptor Nuclear / Coactivador 3 de Receptor Nuclear Límite: Humans Idioma: En Revista: Ecotoxicol Environ Saf Año: 2020 Tipo del documento: Article País de afiliación: China

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