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Characterization of the selective in vitro and in vivo binding properties of crenezumab to oligomeric Aß.
Meilandt, William J; Maloney, Janice A; Imperio, Jose; Lalehzadeh, Guita; Earr, Tim; Crowell, Susan; Bainbridge, Travis W; Lu, Yanmei; Ernst, James A; Fuji, Reina N; Atwal, Jasvinder K.
Afiliación
  • Meilandt WJ; Department of Neuroscience, Genentech, Inc., 1 DNA Way, South San Francisco, CA, 94080, USA.
  • Maloney JA; Department of Neuroscience, Genentech, Inc., 1 DNA Way, South San Francisco, CA, 94080, USA.
  • Imperio J; Department of Neuroscience, Genentech, Inc., 1 DNA Way, South San Francisco, CA, 94080, USA.
  • Lalehzadeh G; Department of Neuroscience, Genentech, Inc., 1 DNA Way, South San Francisco, CA, 94080, USA.
  • Earr T; Department of Neuroscience, Genentech, Inc., 1 DNA Way, South San Francisco, CA, 94080, USA.
  • Crowell S; Department of Preclinical and Translational Pharmacokinetics/Pharmacodynamics, Genentech, Inc., 1 DNA Way, South San Francisco, CA, USA.
  • Bainbridge TW; Department of Protein Chemistry, Genentech, Inc., 1 DNA Way, South San Francisco, CA, USA.
  • Lu Y; Department of Biochemical and Cellular Pharmacology, Genentech, Inc., 1 DNA Way, South San Francisco, CA, USA.
  • Ernst JA; Department of Protein Chemistry, Genentech, Inc., 1 DNA Way, South San Francisco, CA, USA.
  • Fuji RN; Department of Safety Assessment Pathology, Genentech, Inc., 1 DNA Way, South San Francisco, CA, USA.
  • Atwal JK; Department of Neuroscience, Genentech, Inc., 1 DNA Way, South San Francisco, CA, 94080, USA. atwal.jasvinder@gene.com.
Alzheimers Res Ther ; 11(1): 97, 2019 12 01.
Article en En | MEDLINE | ID: mdl-31787113
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Encéfalo / Péptidos beta-Amiloides / Enfermedad de Alzheimer / Anticuerpos Monoclonales Humanizados Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Alzheimers Res Ther Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Encéfalo / Péptidos beta-Amiloides / Enfermedad de Alzheimer / Anticuerpos Monoclonales Humanizados Tipo de estudio: Prognostic_studies Límite: Animals Idioma: En Revista: Alzheimers Res Ther Año: 2019 Tipo del documento: Article País de afiliación: Estados Unidos