Immunomodulatory Effect of Urine-derived Stem Cells on Inflammatory Bowel Diseases via Downregulating Th1/Th17 Immune Responses in a PGE2-dependent Manner.

Zhou, Chi; Wu, Xian-Rui; Liu, Hua-Shan; Liu, Xuan-Hui; Liu, Gui-Hua; Zheng, Xiao-Bin; Hu, Tuo; Liang, Zhen-Xing; He, Xiao-Wen; Wu, Xiao-Jian; Smith, Leona C; Zhang, Yuanyuan; Lan, Ping

Zhou, Chi; Wu, Xian-Rui; Liu, Hua-Shan; Liu, Xuan-Hui; Liu, Gui-Hua; Zheng, Xiao-Bin; Hu, Tuo; Liang, Zhen-Xing; He, Xiao-Wen; Wu, Xiao-Jian; Smith, Leona C; Zhang, Yuanyuan; Lan, Ping.

Afiliación

Zhou C; Department of Colorectal Surgery, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China.
Wu XR; Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China.
Liu HS; Guangzhou Regenerative Medicine and Health Guangdong Laboratory, Guangzhou, China.
Liu XH; Department of Colorectal Surgery, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China.
Liu GH; Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China.
Zheng XB; Guangzhou Regenerative Medicine and Health Guangdong Laboratory, Guangzhou, China.
Hu T; Department of Colorectal Surgery, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China.
Liang ZX; Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China.
He XW; Guangzhou Regenerative Medicine and Health Guangdong Laboratory, Guangzhou, China.
Wu XJ; Department of Colorectal Surgery, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China.
Smith LC; Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China.
Zhang Y; Reproductive Centre, The Sixth Affiliated Hospital of Sun Yat-Sen University, Guangzhou, Guangdong, China.
Lan P; Department of Colorectal Surgery, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China.

J Crohns Colitis ; 14(5): 654-668, 2020 Jun 19.

Article en En | MEDLINE | ID: mdl-31841595

Asunto(s)

Colitis/terapia; Dinoprostona/metabolismo; Inmunomodulación; Enfermedades Inflamatorias del Intestino/inmunología; Células Madre/inmunología; Células TH1/inmunología; Células Th17/inmunología; Adulto; Animales; Células de la Médula Ósea/inmunología; Diferenciación Celular; Proliferación Celular; Células Cultivadas; Técnicas de Cocultivo; Colitis/inducido químicamente; Colitis/patología; Colitis/fisiopatología; Ciclooxigenasa 2/genética; Citocinas/genética; Citocinas/metabolismo; Sulfato de Dextran; Dinoprostona/genética; Regulación hacia Abajo/inmunología; Técnicas de Silenciamiento del Gen; Humanos; Enfermedades Inflamatorias del Intestino/terapia; Activación de Linfocitos; Masculino; Células Madre Mesenquimatosas/inmunología; Ratones; Ratones Endogámicos BALB C; Ratones Endogámicos C57BL; Fitohemaglutininas/farmacología; Trasplante de Células Madre; Células Madre/fisiología; Ácido Trinitrobencenosulfónico; Orina/citología; Adulto Joven

Palabras clave

CD4+ T cells; Urine-derived stem cells; inflammatory bowel diseases

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Células Madre / Dinoprostona / Enfermedades Inflamatorias del Intestino / Colitis / Células TH1 / Inmunomodulación / Células Th17 Idioma: En Revista: J Crohns Colitis Asunto de la revista: GASTROENTEROLOGIA Año: 2020 Tipo del documento: Article País de afiliación: China

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