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Nicotinamide Pathway-Dependent Sirt1 Activation Restores Calcium Homeostasis to Achieve Neuroprotection in Spinocerebellar Ataxia Type 7.
Stoyas, Colleen A; Bushart, David D; Switonski, Pawel M; Ward, Jacqueline M; Alaghatta, Akshay; Tang, Mi-Bo; Niu, Chenchen; Wadhwa, Mandheer; Huang, Haoran; Savchenko, Alex; Gariani, Karim; Xie, Fang; Delaney, Joseph R; Gaasterland, Terry; Auwerx, Johan; Shakkottai, Vikram G; La Spada, Albert R.
Afiliación
  • Stoyas CA; Department of Neurology, Duke University School of Medicine, Durham, NC 27710, USA.
  • Bushart DD; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI 48109, USA; Department of Neurology, University of Michigan, Ann Arbor, MI 48109, USA.
  • Switonski PM; Department of Neurology, Duke University School of Medicine, Durham, NC 27710, USA; Department of Molecular Biomedicine, Institute of Bioorganic Chemistry, Polish Academy of Sciences, Noskowskiego 12/14 Str., 61-704 Poznan, Poland.
  • Ward JM; Department of Pediatrics, University of California, San Diego, La Jolla, CA 92093, USA.
  • Alaghatta A; Department of Neurology, Duke University School of Medicine, Durham, NC 27710, USA.
  • Tang MB; Department of Neurology, Duke University School of Medicine, Durham, NC 27710, USA; Department of Neurology, First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450000 Henan, China.
  • Niu C; Department of Neurology, Duke University School of Medicine, Durham, NC 27710, USA.
  • Wadhwa M; Department of Neurology, Duke University School of Medicine, Durham, NC 27710, USA.
  • Huang H; Department of Neurology, University of Michigan, Ann Arbor, MI 48109, USA.
  • Savchenko A; Department of Pediatrics, University of California, San Diego, La Jolla, CA 92093, USA.
  • Gariani K; Laboratory of Integrative and Systems Physiology, École Polytechnique Fédérale de Lausanne, 1015 Lausanne, Switzerland.
  • Xie F; Department of Pediatrics, University of California, San Diego, La Jolla, CA 92093, USA.
  • Delaney JR; Department of Neurology, Duke University School of Medicine, Durham, NC 27710, USA.
  • Gaasterland T; Institute for Genomic Medicine, University of California, San Diego, La Jolla, CA 92093, USA.
  • Auwerx J; Laboratory of Integrative and Systems Physiology, École Polytechnique Fédérale de Lausanne, 1015 Lausanne, Switzerland.
  • Shakkottai VG; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI 48109, USA; Department of Neurology, University of Michigan, Ann Arbor, MI 48109, USA. Electronic address: vikramsh@med.umich.edu.
  • La Spada AR; Department of Neurology, Duke University School of Medicine, Durham, NC 27710, USA; Department of Pediatrics, University of California, San Diego, La Jolla, CA 92093, USA; Institute for Genomic Medicine, University of California, San Diego, La Jolla, CA 92093, USA; Department of Neurobiology, Duke U
Neuron ; 105(4): 630-644.e9, 2020 02 19.
Article en En | MEDLINE | ID: mdl-31859031
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Calcio / Niacinamida / Ataxias Espinocerebelosas / Sirtuina 1 / Neuroprotección / Homeostasis Límite: Animals / Female / Humans / Male Idioma: En Revista: Neuron Asunto de la revista: NEUROLOGIA Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Calcio / Niacinamida / Ataxias Espinocerebelosas / Sirtuina 1 / Neuroprotección / Homeostasis Límite: Animals / Female / Humans / Male Idioma: En Revista: Neuron Asunto de la revista: NEUROLOGIA Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos