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The acute myeloid leukemia associated AML1-ETO fusion protein alters the transcriptome and cellular progression in a single-oncogene expressing in vitro induced pluripotent stem cell based granulocyte differentiation model.
Tijchon, Esther; Yi, Guoqiang; Mandoli, Amit; Smits, Jos G A; Ferrari, Francesco; Heuts, Branco M H; Wijnen, Falco; Kim, Bowon; Janssen-Megens, Eva M; Schuringa, Jan Jacob; Martens, Joost H A.
Afiliación
  • Tijchon E; Radboud University, Department of Molecular Biology, Faculty of Science, Nijmegen Centre for Molecular Life Sciences, Nijmegen, the Netherlands.
  • Yi G; Radboud University, Department of Molecular Biology, Faculty of Science, Nijmegen Centre for Molecular Life Sciences, Nijmegen, the Netherlands.
  • Mandoli A; Radboud University, Department of Molecular Biology, Faculty of Science, Nijmegen Centre for Molecular Life Sciences, Nijmegen, the Netherlands.
  • Smits JGA; Radboud University, Department of Molecular Biology, Faculty of Science, Nijmegen Centre for Molecular Life Sciences, Nijmegen, the Netherlands.
  • Ferrari F; Radboud University, Department of Molecular Biology, Faculty of Science, Nijmegen Centre for Molecular Life Sciences, Nijmegen, the Netherlands.
  • Heuts BMH; Radboud University, Department of Molecular Biology, Faculty of Science, Nijmegen Centre for Molecular Life Sciences, Nijmegen, the Netherlands.
  • Wijnen F; Radboud University, Department of Molecular Biology, Faculty of Science, Nijmegen Centre for Molecular Life Sciences, Nijmegen, the Netherlands.
  • Kim B; Radboud University, Department of Molecular Biology, Faculty of Science, Nijmegen Centre for Molecular Life Sciences, Nijmegen, the Netherlands.
  • Janssen-Megens EM; Radboud University, Department of Molecular Biology, Faculty of Science, Nijmegen Centre for Molecular Life Sciences, Nijmegen, the Netherlands.
  • Schuringa JJ; Department of Hematology, University Medical Centre Groningen, Groningen, The Netherlands.
  • Martens JHA; Radboud University, Department of Molecular Biology, Faculty of Science, Nijmegen Centre for Molecular Life Sciences, Nijmegen, the Netherlands.
PLoS One ; 14(12): e0226435, 2019.
Article en En | MEDLINE | ID: mdl-31869378
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Proteínas de Fusión Oncogénica / Diferenciación Celular / Transformación Celular Neoplásica / Subunidad alfa 2 del Factor de Unión al Sitio Principal / Células Madre Pluripotentes Inducidas / Transcriptoma / Proteína 1 Compañera de Translocación de RUNX1 / Granulocitos Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: PLoS One Asunto de la revista: CIENCIA / MEDICINA Año: 2019 Tipo del documento: Article País de afiliación: Países Bajos
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Proteínas de Fusión Oncogénica / Diferenciación Celular / Transformación Celular Neoplásica / Subunidad alfa 2 del Factor de Unión al Sitio Principal / Células Madre Pluripotentes Inducidas / Transcriptoma / Proteína 1 Compañera de Translocación de RUNX1 / Granulocitos Tipo de estudio: Prognostic_studies / Risk_factors_studies Límite: Humans Idioma: En Revista: PLoS One Asunto de la revista: CIENCIA / MEDICINA Año: 2019 Tipo del documento: Article País de afiliación: Países Bajos