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Utilization of the chronic atrioventricular block cynomolgus monkey as an in vivo model to evaluate drug interaction-associated torsade de pointes.
Goto, Ai; Sakamoto, Kengo; Hagiwara-Nagasawa, Mihoko; Kambayashi, Ryuichi; Chiba, Koki; Nunoi, Yoshio; Izumi-Nakaseko, Hiroko; Matsumoto, Akio; Sugiyama, Atsushi.
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  • Goto A; Department of Pharmacology, Toho University Graduate School of Medicine, 5-21-16 Omori-nishi, Ota-ku, Tokyo, 143-8540, Japan.
  • Sakamoto K; Ina Research Inc., 2148-188 Nishiminowa, Ina-shi, Nagano, 399-4501, Japan.
  • Hagiwara-Nagasawa M; Department of Pharmacology, Faculty of Medicine, Toho University, 5-21-16 Omori-nishi, Ota-ku, Tokyo, 143-8540, Japan.
  • Kambayashi R; Department of Pharmacology, Faculty of Medicine, Toho University, 5-21-16 Omori-nishi, Ota-ku, Tokyo, 143-8540, Japan.
  • Chiba K; Department of Pharmacology, Toho University Graduate School of Medicine, 5-21-16 Omori-nishi, Ota-ku, Tokyo, 143-8540, Japan.
  • Nunoi Y; Department of Pharmacology, Faculty of Medicine, Toho University, 5-21-16 Omori-nishi, Ota-ku, Tokyo, 143-8540, Japan.
  • Izumi-Nakaseko H; Department of Pharmacology, Toho University Graduate School of Medicine, 5-21-16 Omori-nishi, Ota-ku, Tokyo, 143-8540, Japan; Department of Pharmacology, Faculty of Medicine, Toho University, 5-21-16 Omori-nishi, Ota-ku, Tokyo, 143-8540, Japan.
  • Matsumoto A; Department of Aging Pharmacology, Faculty of Medicine, Toho University, 5-21-16 Omori-nishi, Ota-ku, Tokyo, 143-8540, Japan.
  • Sugiyama A; Department of Pharmacology, Toho University Graduate School of Medicine, 5-21-16 Omori-nishi, Ota-ku, Tokyo, 143-8540, Japan; Department of Pharmacology, Faculty of Medicine, Toho University, 5-21-16 Omori-nishi, Ota-ku, Tokyo, 143-8540, Japan; Department of Aging Pharmacology, Faculty of Medicine,
J Pharmacol Sci ; 142(4): 172-175, 2020 Apr.
Article en En | MEDLINE | ID: mdl-31982331
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Torsades de Pointes / Terfenadina / Modelos Animales de Enfermedad / Sinergismo Farmacológico / Bloqueo Atrioventricular / Cetoconazol Tipo de estudio: Risk_factors_studies Límite: Animals Idioma: En Revista: J Pharmacol Sci Asunto de la revista: FARMACOLOGIA Año: 2020 Tipo del documento: Article País de afiliación: Japón
Texto completo
Imprimir
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PubMed Links
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Torsades de Pointes / Terfenadina / Modelos Animales de Enfermedad / Sinergismo Farmacológico / Bloqueo Atrioventricular / Cetoconazol Tipo de estudio: Risk_factors_studies Límite: Animals Idioma: En Revista: J Pharmacol Sci Asunto de la revista: FARMACOLOGIA Año: 2020 Tipo del documento: Article País de afiliación: Japón