The IUPHAR Guide to Immunopharmacology: connecting immunology and pharmacology.
Immunology
; 160(1): 10-23, 2020 05.
Article
en En
| MEDLINE
| ID: mdl-32020584
ABSTRACT
Given the critical role that the immune system plays in a multitude of diseases, having a clear understanding of the pharmacology of the immune system is crucial to new drug discovery and development. Here we describe the International Union of Basic and Clinical Pharmacology (IUPHAR) Guide to Immunopharmacology (GtoImmuPdb), which connects expert-curated pharmacology with key immunological concepts and aims to put pharmacological data into the hands of immunologists. In the pursuit of new therapeutics, pharmacological databases are a vital resource to researchers through providing accurate information on the fundamental science underlying drug action. This extension to the existing IUPHAR/British Pharmacological Society Guide to Pharmacology supports research into the development of drugs targeted at modulating immune, inflammatory or infectious components of disease. To provide a deeper context for how the resource can support research we show data in GtoImmuPdb relating to a case study on the targeting of vascular inflammation.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Descubrimiento de Drogas
/
Bases de Datos Farmacéuticas
/
Desarrollo de Medicamentos
/
Sistema Inmunológico
/
Factores Inmunológicos
Tipo de estudio:
Clinical_trials
/
Prognostic_studies
Límite:
Humans
Idioma:
En
Revista:
Immunology
Año:
2020
Tipo del documento:
Article
País de afiliación:
Reino Unido