Junior-Real Time neuropsychological testing (j-RTNT) for a young patient undergoing awake craniotomy.
Brain Cogn
; 140: 105535, 2020 04.
Article
en En
| MEDLINE
| ID: mdl-32028087
ABSTRACT
We developed a junior-real-time neuropsychological testing (j-RTNT) and used it during surgery of a right fronto-insular dysembryoplastic neuroepithelial tumor causing seizures in a 16 years old female. The j-RTNT included tasks from the battery NEPSY-II. Pre-surgery evaluation detected a below average performance in visuo-spatial planning, inhibition, visual attention, planning and borderline performance in speeded naming. The j-RTNT allows detecting sudden decreases that could be caused by resection. During surgery, ECoG was characterized by slow sharp activity and spikes on the electrodes exploring the right fronto-polar region. After the resection, spikes were not detected anymore. Immediate post-surgery performance resulted within the normal range, remained below average in visuo-spatial planning, and improved in inhibition, switching and in speeded naming. Follow-up revealed cognitive recovery. Neurological assessment was unremarkable and the patient was seizure free. No epileptic activity could be observed on follow-up EEG. fMRI data showed that in the follow-up vs. pre-surgery there was a higher recruitment of the right superior frontal gyrus, a region involved in the cognitive execution and cognitive control networks. The j-RTNT is feasible with young patients, goes beyond the testing of limited functions, assessing multiple times during resection several different functions to better monitoring the effects of resection.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Corteza Cerebral
/
Craneotomía
/
Epilepsia
/
Disfunción Cognitiva
/
Pruebas Neuropsicológicas
Tipo de estudio:
Etiology_studies
Límite:
Adolescent
/
Female
/
Humans
Idioma:
En
Revista:
Brain Cogn
Año:
2020
Tipo del documento:
Article
País de afiliación:
Italia