COA6 Facilitates Cytochrome c Oxidase Biogenesis as Thiol-reductase for Copper Metallochaperones in Mitochondria.

Pacheu-Grau, David; Wasilewski, Michal; Oeljeklaus, Silke; Gibhardt, Christine Silvia; Aich, Abhishek; Chudenkova, Margarita; Dennerlein, Sven; Deckers, Markus; Bogeski, Ivan; Warscheid, Bettina; Chacinska, Agnieszka; Rehling, Peter

Pacheu-Grau, David; Wasilewski, Michal; Oeljeklaus, Silke; Gibhardt, Christine Silvia; Aich, Abhishek; Chudenkova, Margarita; Dennerlein, Sven; Deckers, Markus; Bogeski, Ivan; Warscheid, Bettina; Chacinska, Agnieszka; Rehling, Peter.

Afiliación

Pacheu-Grau D; Department of Cellular Biochemistry, University Medical Center Göttingen, D-37073 Göttingen, Germany. Electronic address: David.Pacheu-Grau@med.uni-goettingen.de.
Wasilewski M; Laboratory of Mitochondrial Biogenesis, Centre of New Technologies, University of Warsaw, Warsaw, Poland; ReMedy International Research Agenda Unit, Centre of New Technologies, University of Warsaw, Poland.
Oeljeklaus S; Biochemistry and Functional Proteomics, Institute of Biology II, Faculty of Biology, University of Freiburg, D-79104 Freiburg, Germany; Signalling Research Centres BIOSS and CIBSS, University of Freiburg, D-79104 Freiburg, Germany.
Gibhardt CS; Molecular Physiology, Institute of Cardiovascular Physiology, University Medical Center, Georg-August-University, Göttingen, Germany.
Aich A; Department of Cellular Biochemistry, University Medical Center Göttingen, D-37073 Göttingen, Germany.
Chudenkova M; Department of Cellular Biochemistry, University Medical Center Göttingen, D-37073 Göttingen, Germany.
Dennerlein S; Department of Cellular Biochemistry, University Medical Center Göttingen, D-37073 Göttingen, Germany.
Deckers M; Department of Cellular Biochemistry, University Medical Center Göttingen, D-37073 Göttingen, Germany.
Bogeski I; Molecular Physiology, Institute of Cardiovascular Physiology, University Medical Center, Georg-August-University, Göttingen, Germany.
Warscheid B; Biochemistry and Functional Proteomics, Institute of Biology II, Faculty of Biology, University of Freiburg, D-79104 Freiburg, Germany; Signalling Research Centres BIOSS and CIBSS, University of Freiburg, D-79104 Freiburg, Germany.
Chacinska A; Laboratory of Mitochondrial Biogenesis, Centre of New Technologies, University of Warsaw, Warsaw, Poland; ReMedy International Research Agenda Unit, Centre of New Technologies, University of Warsaw, Poland.
Rehling P; Department of Cellular Biochemistry, University Medical Center Göttingen, D-37073 Göttingen, Germany; Max-Planck Institute for Biophysical Chemistry, D-37077 Göttingen, Germany. Electronic address: peter.rehling@medizin.uni-goettingen.de.

J Mol Biol ; 432(7): 2067-2079, 2020 03 27.

Article en En | MEDLINE | ID: mdl-32061935

Asunto(s)

Proteínas Portadoras/metabolismo; Cobre/metabolismo; Proteínas del Complejo de Cadena de Transporte de Electrón/metabolismo; Mitocondrias/metabolismo; Proteínas Mitocondriales/metabolismo; Chaperonas Moleculares/metabolismo; Compuestos de Sulfhidrilo/química; Proteínas Portadoras/genética; Transporte de Electrón; Proteínas del Complejo de Cadena de Transporte de Electrón/genética; Células HEK293; Humanos; Metalochaperonas; Mitocondrias/genética; Proteínas Mitocondriales/genética; Chaperonas Moleculares/genética; Mutación; Transporte de Proteínas

Palabras clave

COA6; Cu(A) center; copper metallochaperones; cytochrome c oxidase; mitochondria

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Compuestos de Sulfhidrilo / Proteínas Portadoras / Chaperonas Moleculares / Cobre / Proteínas Mitocondriales / Proteínas del Complejo de Cadena de Transporte de Electrón / Mitocondrias Límite: Humans Idioma: En Revista: J Mol Biol Año: 2020 Tipo del documento: Article

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