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Mechanism of proton transfer in class A ß-lactamase catalysis and inhibition by avibactam.
Pemberton, Orville A; Noor, Radwan E; Kumar M V, Vasantha; Sanishvili, Ruslan; Kemp, M Trent; Kearns, Fiona L; Woodcock, H Lee; Gelis, Ioannis; Chen, Yu.
Afiliación
  • Pemberton OA; Department of Molecular Medicine, University of South Florida, Tampa, FL 33612.
  • Noor RE; Department of Chemistry, University of South Florida, Tampa, FL 33620.
  • Kumar M V V; Department of Chemistry, University of South Florida, Tampa, FL 33620.
  • Sanishvili R; GM/CA@APS, X-ray Science Division, Advanced Photon Source, Argonne National Laboratory, Argonne, IL 60439.
  • Kemp MT; Department of Molecular Medicine, University of South Florida, Tampa, FL 33612.
  • Kearns FL; Department of Chemistry, University of South Florida, Tampa, FL 33620.
  • Woodcock HL; Department of Chemistry, University of South Florida, Tampa, FL 33620.
  • Gelis I; Department of Chemistry, University of South Florida, Tampa, FL 33620; igelis@usf.edu ychen1@health.usf.edu.
  • Chen Y; Department of Molecular Medicine, University of South Florida, Tampa, FL 33612; igelis@usf.edu ychen1@health.usf.edu.
Proc Natl Acad Sci U S A ; 117(11): 5818-5825, 2020 03 17.
Article en En | MEDLINE | ID: mdl-32123084
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Protones / Beta-Lactamasas / Compuestos de Azabiciclo / Inhibidores de beta-Lactamasas Tipo de estudio: Prognostic_studies Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2020 Tipo del documento: Article
Texto completo
Imprimir
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PubMed Links
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Protones / Beta-Lactamasas / Compuestos de Azabiciclo / Inhibidores de beta-Lactamasas Tipo de estudio: Prognostic_studies Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2020 Tipo del documento: Article