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Bridge helix arginines play a critical role in Cas9 sensitivity to mismatches.
Bratovic, Majda; Fonfara, Ines; Chylinski, Krzysztof; Gálvez, Eric J C; Sullivan, Timothy J; Boerno, Stefan; Timmermann, Bernd; Boettcher, Michael; Charpentier, Emmanuelle.
Afiliación
  • Bratovic M; Max Planck Unit for the Science of Pathogens, Berlin, Germany.
  • Fonfara I; Department of Regulation in Infection Biology, Max Planck Institute for Infection Biology, Berlin, Germany.
  • Chylinski K; Institute for Biology, Humboldt University, Berlin, Germany.
  • Gálvez EJC; Department of Regulation in Infection Biology, Helmholtz Centre for Infection Research, Braunschweig, Germany.
  • Sullivan TJ; Department of Regulation in Infection Biology, Max Planck Institute for Infection Biology, Berlin, Germany.
  • Boerno S; Department of Regulation in Infection Biology, Helmholtz Centre for Infection Research, Braunschweig, Germany.
  • Timmermann B; The Laboratory for Molecular Infection Medicine Sweden, Umeå Centre for Microbial Research, Department of Molecular Biology, Umeå University, Umeå, Sweden.
  • Boettcher M; The Laboratory for Molecular Infection Medicine Sweden, Umeå Centre for Microbial Research, Department of Molecular Biology, Umeå University, Umeå, Sweden.
  • Charpentier E; Max F. Perutz Laboratories, University of Vienna, Vienna, Austria.
Nat Chem Biol ; 16(5): 587-595, 2020 05.
Article en En | MEDLINE | ID: mdl-32123387
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Arginina / Proteína 9 Asociada a CRISPR Tipo de estudio: Diagnostic_studies Límite: Humans Idioma: En Revista: Nat Chem Biol Asunto de la revista: BIOLOGIA / QUIMICA Año: 2020 Tipo del documento: Article País de afiliación: Alemania
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Arginina / Proteína 9 Asociada a CRISPR Tipo de estudio: Diagnostic_studies Límite: Humans Idioma: En Revista: Nat Chem Biol Asunto de la revista: BIOLOGIA / QUIMICA Año: 2020 Tipo del documento: Article País de afiliación: Alemania