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Intestinal bile acids directly modulate the structure and function of C. difficile TcdB toxin.
Tam, John; Icho, Simoun; Utama, Evelyn; Orrell, Kathleen E; Gómez-Biagi, Rodolfo F; Theriot, Casey M; Kroh, Heather K; Rutherford, Stacey A; Lacy, D Borden; Melnyk, Roman A.
Afiliación
  • Tam J; Molecular Medicine, Research Institute, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada.
  • Icho S; Molecular Medicine, Research Institute, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada.
  • Utama E; Department of Biochemistry, University of Toronto, Toronto, ON M5S 1A8, Canada.
  • Orrell KE; Molecular Medicine, Research Institute, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada.
  • Gómez-Biagi RF; Department of Biochemistry, University of Toronto, Toronto, ON M5S 1A8, Canada.
  • Theriot CM; Department of Biochemistry, University of Toronto, Toronto, ON M5S 1A8, Canada.
  • Kroh HK; Molecular Medicine, Research Institute, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada.
  • Rutherford SA; SickKids Proteomics Analytics Robotics Chemical Biology Drug Discovery Facility, Research Institute, Hospital for Sick Children, Toronto, ON M5G 0A4, Canada.
  • Lacy DB; Department of Population Health and Pathobiology, College of Veterinary Medicine, North Carolina State University, Raleigh, NC 27606.
  • Melnyk RA; Department of Pathology, Microbiology, and Immunology, Vanderbilt University School of Medicine, Nashville, TN 37232.
Proc Natl Acad Sci U S A ; 117(12): 6792-6800, 2020 03 24.
Article en En | MEDLINE | ID: mdl-32152097
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Toxinas Bacterianas / Ácidos y Sales Biliares / Clostridioides difficile / Receptores de Superficie Celular / Intestinos Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2020 Tipo del documento: Article País de afiliación: Canadá
Texto completo
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XML
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Toxinas Bacterianas / Ácidos y Sales Biliares / Clostridioides difficile / Receptores de Superficie Celular / Intestinos Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Año: 2020 Tipo del documento: Article País de afiliación: Canadá