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Guselkumab in patients with active psoriatic arthritis who were biologic-naive or had previously received TNFα inhibitor treatment (DISCOVER-1): a double-blind, randomised, placebo-controlled phase 3 trial.
Deodhar, Atul; Helliwell, Philip S; Boehncke, Wolf-Henning; Kollmeier, Alexa P; Hsia, Elizabeth C; Subramanian, Ramanand A; Xu, Xie L; Sheng, Shihong; Agarwal, Prasheen; Zhou, Bei; Zhuang, Yanli; Ritchlin, Christopher T.
Afiliación
  • Deodhar A; Division of Arthritis and Rheumatic Diseases, Oregon Health and Science University, Portland, OR, USA. Electronic address: deodhara@ohsu.edu.
  • Helliwell PS; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK; National Institute for Health Research Leeds Musculoskeletal Biomedical Research Centre, Leeds, UK.
  • Boehncke WH; Division of Dermatology and Venerology, Geneva University Hospitals, Geneva, Switzerland.
  • Kollmeier AP; Immunology, Janssen Research and Development, San Diego, CA, USA.
  • Hsia EC; Immunology, Janssen Research and Development, Spring House, PA, USA; University of Pennsylvania Medical Center, Philadelphia, PA, USA.
  • Subramanian RA; Immunology, Janssen Research and Development, Spring House, PA, USA.
  • Xu XL; Immunology, Janssen Research and Development, San Diego, CA, USA.
  • Sheng S; Clinical Biostatistics, Janssen Research and Development, Spring House, PA, USA.
  • Agarwal P; Clinical Biostatistics, Janssen Research and Development, Spring House, PA, USA.
  • Zhou B; Clinical Biostatistics, Janssen Research and Development, Spring House, PA, USA.
  • Zhuang Y; Clinical Pharmacology and Pharmacometrics, Janssen Research and Development, Spring House, PA, USA.
  • Ritchlin CT; Allergy, Immunology, and Rheumatology, University of Rochester Medical Center, Rochester, NY, USA.
Lancet ; 395(10230): 1115-1125, 2020 04 04.
Article en En | MEDLINE | ID: mdl-32178765
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Artritis Psoriásica / Factor de Necrosis Tumoral alfa / Anticuerpos Monoclonales Humanizados Tipo de estudio: Clinical_trials Límite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Lancet Año: 2020 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Artritis Psoriásica / Factor de Necrosis Tumoral alfa / Anticuerpos Monoclonales Humanizados Tipo de estudio: Clinical_trials Límite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Lancet Año: 2020 Tipo del documento: Article