Novel BCL2 mutations in venetoclax-resistant, ibrutinib-resistant CLL patients with BTK/PLCG2 mutations.

Lucas, Fabienne; Larkin, Karylin; Gregory, C Thomas; Orwick, Shelley; Doong, Tzyy-Jye; Lozanski, Arletta; Lozanski, Gerard; Misra, Shrilekha; Ngankeu, Apollinaire; Ozer, Hatice Gulcin; Sampath, Deepa; Thangavadivel, Shanmugapriya; Yilmaz, Selen A; Rogers, Kerry A; Byrd, John C; Woyach, Jennifer A; Blachly, James S

Lucas, Fabienne; Larkin, Karylin; Gregory, C Thomas; Orwick, Shelley; Doong, Tzyy-Jye; Lozanski, Arletta; Lozanski, Gerard; Misra, Shrilekha; Ngankeu, Apollinaire; Ozer, Hatice Gulcin; Sampath, Deepa; Thangavadivel, Shanmugapriya; Yilmaz, Selen A; Rogers, Kerry A; Byrd, John C; Woyach, Jennifer A; Blachly, James S.

Afiliación

Lucas F; Division of Hematology, Department of Internal Medicine.
Larkin K; The Ohio State University Comprehensive Cancer Center.
Gregory CT; Division of Hematology, Department of Internal Medicine.
Orwick S; The Ohio State University Comprehensive Cancer Center.
Doong TJ; Division of Hematology, Department of Internal Medicine.
Lozanski A; The Ohio State University Comprehensive Cancer Center.
Lozanski G; Division of Hematology, Department of Internal Medicine.
Misra S; The Ohio State University Comprehensive Cancer Center.
Ngankeu A; Division of Hematology, Department of Internal Medicine.
Ozer HG; The Ohio State University Comprehensive Cancer Center.
Sampath D; Division of Hematology, Department of Internal Medicine.
Thangavadivel S; The Ohio State University Comprehensive Cancer Center.
Yilmaz SA; Department of Pathology.
Rogers KA; Division of Hematology, Department of Internal Medicine.
Byrd JC; The Ohio State University Comprehensive Cancer Center.
Woyach JA; Division of Hematology, Department of Internal Medicine.
Blachly JS; The Ohio State University Comprehensive Cancer Center.

Blood ; 135(24): 2192-2195, 2020 06 11.

Article en En | MEDLINE | ID: mdl-32232486

Asunto(s)

Agammaglobulinemia Tirosina Quinasa/genética; Resistencia a Antineoplásicos/genética; Leucemia Linfocítica Crónica de Células B/tratamiento farmacológico; Leucemia Linfocítica Crónica de Células B/genética; Mutación; Fosfolipasa C gamma/genética; Proteínas Proto-Oncogénicas c-bcl-2/genética; Adenina/análogos & derivados; Adenina/uso terapéutico; Anciano; Antineoplásicos/uso terapéutico; Compuestos Bicíclicos Heterocíclicos con Puentes/uso terapéutico; Femenino; Humanos; Masculino; Persona de Mediana Edad; Terapia Molecular Dirigida; Piperidinas/uso terapéutico; Sulfonamidas/uso terapéutico

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Leucemia Linfocítica Crónica de Células B / Resistencia a Antineoplásicos / Proteínas Proto-Oncogénicas c-bcl-2 / Fosfolipasa C gamma / Agammaglobulinemia Tirosina Quinasa / Mutación Límite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Blood Año: 2020 Tipo del documento: Article

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