A novel virtual barcode strategy for accurate panel-wide variant calling in circulating tumor DNA.

Wu, Leilei; Deng, Qinfang; Xu, Ze; Zhou, Songwen; Li, Chao; Li, Yi-Xue

Wu, Leilei; Deng, Qinfang; Xu, Ze; Zhou, Songwen; Li, Chao; Li, Yi-Xue.

Afiliación

Wu L; School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, Shanghai, 200240, China.
Deng Q; Department of Oncology, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, 200433, China.
Xu Z; Smartquerier Biomedicine, Shanghai, 201203, China.
Zhou S; Department of Oncology, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, 200433, China. songwenzhou2017@vip.126.com.
Li C; Smartquerier Biomedicine, Shanghai, 201203, China. lichao@smartquerier.com.
Li YX; Shanghai Center for Bioinformation Technology, Shanghai, 201203, China. lichao@smartquerier.com.

BMC Bioinformatics ; 21(1): 127, 2020 Apr 03.

Article en En | MEDLINE | ID: mdl-32245364

Asunto(s)

Algoritmos; ADN Tumoral Circulante/química; Análisis de Secuencia de ADN/métodos; Simulación por Computador; Humanos; Mutación

Palabras clave

Low-AF SNV; Panel-wide calling algorithm; Stereotypical noise; Stochastic noise; Virtual barcode; ctDNA

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Algoritmos / Análisis de Secuencia de ADN / ADN Tumoral Circulante Tipo de estudio: Prognostic_studies Límite: Humans Idioma: En Revista: BMC Bioinformatics Asunto de la revista: INFORMATICA MEDICA Año: 2020 Tipo del documento: Article País de afiliación: China

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