Congenital virilization of female infants recognized after pregnancies with retained levonorgestrel intrauterine devices.
J Pediatr Urol
; 16(2): 241-243, 2020 04.
Article
en En
| MEDLINE
| ID: mdl-32265103
ABSTRACT
The Mirena intrauterine device (IUD) is a hormone-secreting contraceptive device. Pregnancy with the Mirena is rare and effects to the fetus are unknown. Here we present four females with genital virilization after pregnancy with persistent Mirena IUD. All patients had a 46, XX karyotype and normal hormone evaluation. All underwent exam under anesthesia, demonstrating posterior labial fusion and short urogenital sinus with normal bladder, urethra, vagina, and cervix. Three of four patients underwent flap vaginoplasty without complications and good cosmetic outcomes. This series suggests that persistent levonorgestrel-secreting IUD during pregnancy is associated with genital virilization in female fetuses.
Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Levonorgestrel
/
Dispositivos Intrauterinos Medicados
Límite:
Female
/
Humans
/
Infant
/
Pregnancy
Idioma:
En
Revista:
J Pediatr Urol
Año:
2020
Tipo del documento:
Article