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Challenging the challenge: A randomized controlled trial evaluating the inflammatory response and pain perception of healthy volunteers after single-dose LPS administration, as a potential model for inflammatory pain in early-phase drug development.
Hijma, H J; Moss, L M; Gal, P; Ziagkos, D; de Kam, M L; Moerland, M; Groeneveld, G J.
Afiliación
  • Hijma HJ; Centre for Human Drug Research, 2333 CL Leiden, The Netherlands; Leiden University Medical Centre, 2333 ZA Leiden, The Netherlands. Electronic address: hhijma@chdr.nl.
  • Moss LM; Centre for Human Drug Research, 2333 CL Leiden, The Netherlands; Leiden University Medical Centre, 2333 ZA Leiden, The Netherlands. Electronic address: lmoss@chdr.nl.
  • Gal P; Centre for Human Drug Research, 2333 CL Leiden, The Netherlands; Leiden University Medical Centre, 2333 ZA Leiden, The Netherlands. Electronic address: pgal@chdr.nl.
  • Ziagkos D; Centre for Human Drug Research, 2333 CL Leiden, The Netherlands. Electronic address: dziagkos@chdr.nl.
  • de Kam ML; Centre for Human Drug Research, 2333 CL Leiden, The Netherlands. Electronic address: mdekam@chdr.nl.
  • Moerland M; Centre for Human Drug Research, 2333 CL Leiden, The Netherlands; Leiden University Medical Centre, 2333 ZA Leiden, The Netherlands. Electronic address: mmoerland@chdr.nl.
  • Groeneveld GJ; Centre for Human Drug Research, 2333 CL Leiden, The Netherlands; Leiden University Medical Centre, 2333 ZA Leiden, The Netherlands. Electronic address: GGroeneveld@chdr.nl.
Brain Behav Immun ; 88: 515-528, 2020 08.
Article en En | MEDLINE | ID: mdl-32305572
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Dolor Tipo de estudio: Clinical_trials / Prognostic_studies Límite: Humans / Male Idioma: En Revista: Brain Behav Immun Asunto de la revista: ALERGIA E IMUNOLOGIA / CEREBRO / PSICOFISIOLOGIA Año: 2020 Tipo del documento: Article
Texto completo
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Dolor Tipo de estudio: Clinical_trials / Prognostic_studies Límite: Humans / Male Idioma: En Revista: Brain Behav Immun Asunto de la revista: ALERGIA E IMUNOLOGIA / CEREBRO / PSICOFISIOLOGIA Año: 2020 Tipo del documento: Article