Blood Vitronectin Induces Detrimental Brain Interleukin-6 and Correlates With Outcomes After Stroke Only in Female Mice.

Jia, Cuihong; Malone, Hannah M; Keasey, Matthew P; Lovins, Chiharu; Elam, Jacob; Hagg, Theo

Jia, Cuihong; Malone, Hannah M; Keasey, Matthew P; Lovins, Chiharu; Elam, Jacob; Hagg, Theo.

Afiliación

Jia C; From the Department of Biomedical Sciences, Quillen College of Medicine, East Tennessee State University, Johnson City.
Malone HM; From the Department of Biomedical Sciences, Quillen College of Medicine, East Tennessee State University, Johnson City.
Keasey MP; From the Department of Biomedical Sciences, Quillen College of Medicine, East Tennessee State University, Johnson City.
Lovins C; From the Department of Biomedical Sciences, Quillen College of Medicine, East Tennessee State University, Johnson City.
Elam J; From the Department of Biomedical Sciences, Quillen College of Medicine, East Tennessee State University, Johnson City.
Hagg T; From the Department of Biomedical Sciences, Quillen College of Medicine, East Tennessee State University, Johnson City.

Stroke ; 51(5): 1587-1595, 2020 05.

Article en En | MEDLINE | ID: mdl-32312218

Asunto(s)

Barrera Hematoencefálica/metabolismo; Infarto de la Arteria Cerebral Media/genética; Inflamación/genética; Interleucina-6/genética; Vitronectina/genética; Animales; Factor Neurotrófico Ciliar/genética; Factor Neurotrófico Ciliar/metabolismo; Femenino; Infarto de la Arteria Cerebral Media/metabolismo; Infarto de la Arteria Cerebral Media/patología; Infarto de la Arteria Cerebral Media/fisiopatología; Inflamación/metabolismo; Interleucina-6/metabolismo; Factor Inhibidor de Leucemia/genética; Factor Inhibidor de Leucemia/metabolismo; Macrófagos/metabolismo; Macrófagos/patología; Masculino; Ratones; Ratones Noqueados; Microglía/metabolismo; Microglía/patología; ARN Mensajero/metabolismo; Factores Sexuales; Accidente Cerebrovascular/genética; Accidente Cerebrovascular/metabolismo; Accidente Cerebrovascular/patología; Accidente Cerebrovascular/fisiopatología; Vitronectina/sangre; Vitronectina/metabolismo

Palabras clave

blood; cell death; inflammation; ischemia; mice; sex characteristics; stroke

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Barrera Hematoencefálica / Interleucina-6 / Vitronectina / Infarto de la Arteria Cerebral Media / Inflamación Límite: Animals Idioma: En Revista: Stroke Año: 2020 Tipo del documento: Article

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