Enzyme-Triggered Disassembly of Perylene Monoimide-based Nanoclusters for Activatable and Deep Photodynamic Therapy.

Cai, Yang; Ni, Dongqi; Cheng, Wenyu; Ji, Chendong; Wang, Yaling; Müllen, Klaus; Su, Zhiqiang; Liu, Ying; Chen, Chunying; Yin, Meizhen

Cai, Yang; Ni, Dongqi; Cheng, Wenyu; Ji, Chendong; Wang, Yaling; Müllen, Klaus; Su, Zhiqiang; Liu, Ying; Chen, Chunying; Yin, Meizhen.

Afiliación

Cai Y; State Key Laboratory of Chemical Resource Engineering, Beijing Advanced Innovation Center for Soft Matter Science and Engineering, Beijing Laboratory of Biomedical Materials, Beijing University of Chemical Technology, Beijing, 100029, China.
Ni D; CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology, University of Chinese Academy of Sciences, Beijing, 100190, China.
Cheng W; State Key Laboratory of Chemical Resource Engineering, Beijing Advanced Innovation Center for Soft Matter Science and Engineering, Beijing Laboratory of Biomedical Materials, Beijing University of Chemical Technology, Beijing, 100029, China.
Ji C; State Key Laboratory of Chemical Resource Engineering, Beijing Advanced Innovation Center for Soft Matter Science and Engineering, Beijing Laboratory of Biomedical Materials, Beijing University of Chemical Technology, Beijing, 100029, China.
Wang Y; CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology, University of Chinese Academy of Sciences, Beijing, 100190, China.
Müllen K; Max Planck Institute for Polymer Research, Ackermannweg 10, 55128, Mainz, Germany.
Su Z; State Key Laboratory of Chemical Resource Engineering, Beijing Advanced Innovation Center for Soft Matter Science and Engineering, Beijing Laboratory of Biomedical Materials, Beijing University of Chemical Technology, Beijing, 100029, China.
Liu Y; CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology, University of Chinese Academy of Sciences, Beijing, 100190, China.
Chen C; CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology, University of Chinese Academy of Sciences, Beijing, 100190, China.
Yin M; State Key Laboratory of Chemical Resource Engineering, Beijing Advanced Innovation Center for Soft Matter Science and Engineering, Beijing Laboratory of Biomedical Materials, Beijing University of Chemical Technology, Beijing, 100029, China.

Angew Chem Int Ed Engl ; 59(33): 14014-14018, 2020 08 10.

Article en En | MEDLINE | ID: mdl-32363672

Asunto(s)

Hidrolasas de Éster Carboxílico/metabolismo; Imidas/química; Nanoestructuras; Perileno/química; Fotoquimioterapia/métodos; Animales; Línea Celular Tumoral; Humanos; Ratones; Fármacos Fotosensibilizantes/farmacología

Palabras clave

NIR fluorescence imaging; activatable photodynamic therapy; deep tumor penetration; enzyme-triggered disassembly; perylene monoimide

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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Perileno / Fotoquimioterapia / Hidrolasas de Éster Carboxílico / Nanoestructuras / Imidas Límite: Animals / Humans Idioma: En Revista: Angew Chem Int Ed Engl Año: 2020 Tipo del documento: Article País de afiliación: China

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