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The CEP5 Peptide Promotes Abiotic Stress Tolerance, As Revealed by Quantitative Proteomics, and Attenuates the AUX/IAA Equilibrium in Arabidopsis.
Smith, Stephanie; Zhu, Shanshuo; Joos, Lisa; Roberts, Ianto; Nikonorova, Natalia; Vu, Lam Dai; Stes, Elisabeth; Cho, Hyunwoo; Larrieu, Antoine; Xuan, Wei; Goodall, Benjamin; van de Cotte, Brigitte; Waite, Jessic Marie; Rigal, Adeline; Ramans Harborough, Sigurd; Persiau, Geert; Vanneste, Steffen; Kirschner, Gwendolyn K; Vandermarliere, Elien; Martens, Lennart; Stahl, Yvonne; Audenaert, Dominique; Friml, Jirí; Felix, Georg; Simon, Rüdiger; Bennett, Malcolm J; Bishopp, Anthony; De Jaeger, Geert; Ljung, Karin; Kepinski, Stefan; Robert, Stephanie; Nemhauser, Jennifer; Hwang, Ildoo; Gevaert, Kris; Beeckman, Tom; De Smet, Ive.
Afiliación
  • Smith S; Division of Plant and Crop Sciences, School of Biosciences, University of Nottingham, Loughborough, United Kingdom.
  • Zhu S; Department of Plant Biotechnology and Bioinformatics, Ghent University, Belgium; VIB Center for Plant Systems Biology, Ghent, Belgium; VIB-UGent Center for Medical Biotechnology, Ghent, Belgium; Department of Biomolecular Medicine, Ghent University, Ghent, Belgium.
  • Joos L; Department of Plant Biotechnology and Bioinformatics, Ghent University, Belgium; VIB Center for Plant Systems Biology, Ghent, Belgium.
  • Roberts I; Department of Plant Biotechnology and Bioinformatics, Ghent University, Belgium; VIB Center for Plant Systems Biology, Ghent, Belgium.
  • Nikonorova N; Department of Plant Biotechnology and Bioinformatics, Ghent University, Belgium; VIB Center for Plant Systems Biology, Ghent, Belgium.
  • Vu LD; Department of Plant Biotechnology and Bioinformatics, Ghent University, Belgium; VIB Center for Plant Systems Biology, Ghent, Belgium; VIB-UGent Center for Medical Biotechnology, Ghent, Belgium; Department of Biomolecular Medicine, Ghent University, Ghent, Belgium.
  • Stes E; Department of Plant Biotechnology and Bioinformatics, Ghent University, Belgium; VIB Center for Plant Systems Biology, Ghent, Belgium; VIB-UGent Center for Medical Biotechnology, Ghent, Belgium; Department of Biomolecular Medicine, Ghent University, Ghent, Belgium.
  • Cho H; Department of Life Sciences, POSTECH Biotech Center, Pohang University of Science and Technology, Pohang, Republic of Korea.
  • Larrieu A; Centre for Plant Integrative Biology, University of Nottingham, Loughborough, United Kingdom.
  • Xuan W; Department of Plant Biotechnology and Bioinformatics, Ghent University, Belgium; VIB Center for Plant Systems Biology, Ghent, Belgium.
  • Goodall B; Centre for Plant Integrative Biology, University of Nottingham, Loughborough, United Kingdom.
  • van de Cotte B; Department of Plant Biotechnology and Bioinformatics, Ghent University, Belgium; VIB Center for Plant Systems Biology, Ghent, Belgium.
  • Waite JM; Department of Biology, University of Washington, Seattle, Washington, USA.
  • Rigal A; Umeå Plant Science Centre, Department of Forest Genetics and Plant Physiology, Swedish University of Agricultural Sciences, Umeå, Sweden.
  • Ramans Harborough S; Centre for Plant Sciences, Faculty of Biological Sciences, University of Leeds, Leeds, United Kingdom.
  • Persiau G; Department of Plant Biotechnology and Bioinformatics, Ghent University, Belgium; VIB Center for Plant Systems Biology, Ghent, Belgium.
  • Vanneste S; Department of Plant Biotechnology and Bioinformatics, Ghent University, Belgium; VIB Center for Plant Systems Biology, Ghent, Belgium.
  • Kirschner GK; Institute for Developmental Genetics, Heinrich-Heine University, Düsseldorf, Germany.
  • Vandermarliere E; VIB-UGent Center for Medical Biotechnology, Ghent, Belgium; Department of Biomolecular Medicine, Ghent University, Ghent, Belgium.
  • Martens L; VIB-UGent Center for Medical Biotechnology, Ghent, Belgium; Department of Biomolecular Medicine, Ghent University, Ghent, Belgium.
  • Stahl Y; Institute for Developmental Genetics, Heinrich-Heine University, Düsseldorf, Germany.
  • Audenaert D; Screening Core, Gent, Belgium; Expertise Centre for Bioassay Development and Screening (C-BIOS), Ghent University, Ghent, Belgium.
  • Friml J; Mendel Centre for Plant Genomics and Proteomics, Central European Institute of Technology (CEITEC), Masaryk University (MU), Brno, Czech Republic; Institute of Science and Technology Austria (IST Austria), Klosterneuburg, Austria.
  • Felix G; Zentrum für Molekularbiologie der Pflanzen, Plant Biochemistry, University Tübingen, Tübingen, Germany.
  • Simon R; Institute for Developmental Genetics, Heinrich-Heine University, Düsseldorf, Germany.
  • Bennett MJ; Division of Plant and Crop Sciences, School of Biosciences, University of Nottingham, Loughborough, United Kingdom; Centre for Plant Integrative Biology, University of Nottingham, Loughborough, United Kingdom.
  • Bishopp A; Centre for Plant Integrative Biology, University of Nottingham, Loughborough, United Kingdom.
  • De Jaeger G; Department of Plant Biotechnology and Bioinformatics, Ghent University, Belgium; VIB Center for Plant Systems Biology, Ghent, Belgium.
  • Ljung K; Umeå Plant Science Centre, Department of Forest Genetics and Plant Physiology, Swedish University of Agricultural Sciences, Umeå, Sweden.
  • Kepinski S; Centre for Plant Sciences, Faculty of Biological Sciences, University of Leeds, Leeds, United Kingdom.
  • Robert S; Umeå Plant Science Centre, Department of Forest Genetics and Plant Physiology, Swedish University of Agricultural Sciences, Umeå, Sweden.
  • Nemhauser J; Department of Biology, University of Washington, Seattle, Washington, USA.
  • Hwang I; Department of Life Sciences, POSTECH Biotech Center, Pohang University of Science and Technology, Pohang, Republic of Korea.
  • Gevaert K; VIB-UGent Center for Medical Biotechnology, Ghent, Belgium; Department of Biomolecular Medicine, Ghent University, Ghent, Belgium.
  • Beeckman T; Department of Plant Biotechnology and Bioinformatics, Ghent University, Belgium; VIB Center for Plant Systems Biology, Ghent, Belgium.
  • De Smet I; Division of Plant and Crop Sciences, School of Biosciences, University of Nottingham, Loughborough, United Kingdom; Department of Plant Biotechnology and Bioinformatics, Ghent University, Belgium; VIB Center for Plant Systems Biology, Ghent, Belgium; Centre for Plant Integrative Biology, University
Mol Cell Proteomics ; 19(8): 1248-1262, 2020 08.
Article en En | MEDLINE | ID: mdl-32404488
Peptides derived from non-functional precursors play important roles in various developmental processes, but also in (a)biotic stress signaling. Our (phospho)proteome-wide analyses of C-TERMINALLY ENCODED PEPTIDE 5 (CEP5)-mediated changes revealed an impact on abiotic stress-related processes. Drought has a dramatic impact on plant growth, development and reproduction, and the plant hormone auxin plays a role in drought responses. Our genetic, physiological, biochemical, and pharmacological results demonstrated that CEP5-mediated signaling is relevant for osmotic and drought stress tolerance in Arabidopsis, and that CEP5 specifically counteracts auxin effects. Specifically, we found that CEP5 signaling stabilizes AUX/IAA transcriptional repressors, suggesting the existence of a novel peptide-dependent control mechanism that tunes auxin signaling. These observations align with the recently described role of AUX/IAAs in stress tolerance and provide a novel role for CEP5 in osmotic and drought stress tolerance.
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Péptidos / Estrés Fisiológico / Adaptación Fisiológica / Arabidopsis / Proteínas de Arabidopsis / Proteómica / Ácidos Indolacéticos Idioma: En Revista: Mol Cell Proteomics Asunto de la revista: BIOLOGIA MOLECULAR / BIOQUIMICA Año: 2020 Tipo del documento: Article País de afiliación: Reino Unido

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Péptidos / Estrés Fisiológico / Adaptación Fisiológica / Arabidopsis / Proteínas de Arabidopsis / Proteómica / Ácidos Indolacéticos Idioma: En Revista: Mol Cell Proteomics Asunto de la revista: BIOLOGIA MOLECULAR / BIOQUIMICA Año: 2020 Tipo del documento: Article País de afiliación: Reino Unido