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Nascent transcript and single-cell RNA-seq analysis defines the mechanism of action of the LSD1 inhibitor INCB059872 in myeloid leukemia.
Johnston, Gretchen; Ramsey, Haley E; Liu, Qi; Wang, Jing; Stengel, Kristy R; Sampathi, Shilpa; Acharya, Pankaj; Arrate, Maria; Stubbs, Matthew C; Burn, Timothy; Savona, Michael R; Hiebert, Scott W.
Afiliación
  • Johnston G; Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.
  • Ramsey HE; Department of Medicine and Program in Cancer Biology, Vanderbilt University School of Medicine, Nashville, TN 37203, USA.
  • Liu Q; Department of Biostatistics, Vanderbilt University School of Medicine, Nashville, TN 37203, USA; Center for Quantitative Sciences, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
  • Wang J; Department of Biostatistics, Vanderbilt University School of Medicine, Nashville, TN 37203, USA; Center for Quantitative Sciences, Vanderbilt University Medical Center, Nashville, TN 37232, USA.
  • Stengel KR; Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.
  • Sampathi S; Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.
  • Acharya P; Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.
  • Arrate M; Department of Medicine and Program in Cancer Biology, Vanderbilt University School of Medicine, Nashville, TN 37203, USA.
  • Stubbs MC; Incyte Corporation, Wilmington, DE 19803, USA.
  • Burn T; Incyte Corporation, Wilmington, DE 19803, USA.
  • Savona MR; Department of Medicine and Program in Cancer Biology, Vanderbilt University School of Medicine, Nashville, TN 37203, USA; Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN 37027, USA.
  • Hiebert SW; Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, TN 37232, USA; Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN 37027, USA. Electronic address: scott.hiebert@vanderbilt.edu.
Gene ; 752: 144758, 2020 Aug 20.
Article en En | MEDLINE | ID: mdl-32422235
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Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Leucemia Mieloide Aguda / Regulación Leucémica de la Expresión Génica / Histona Demetilasas Límite: Animals / Female / Humans Idioma: En Revista: Gene Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos
Texto completo
Imprimir
XML
PubMed Links
Buscar en Google

Texto completo: 1 Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Leucemia Mieloide Aguda / Regulación Leucémica de la Expresión Génica / Histona Demetilasas Límite: Animals / Female / Humans Idioma: En Revista: Gene Año: 2020 Tipo del documento: Article País de afiliación: Estados Unidos