RGEN Editing of RNA and DNA: The Long and Winding Road from Catalytic RNAs to CRISPR to the Clinic.
Cell
; 181(5): 955-960, 2020 05 28.
Article
en En
| MEDLINE
| ID: mdl-32470403
The first clinical studies utilizing RNA-guided endonucleases (RGENs) to therapeutically edit RNA and DNA in cancer patients were recently published. These groundbreaking technological advances promise to revolutionize genetic therapy and, as I discuss, represent the culmination of decades of innovative work to engineer RGENs for such editing applications.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Edición de ARN
/
Edición Génica
Idioma:
En
Revista:
Cell
Año:
2020
Tipo del documento:
Article